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Formation of multimeric antibodies for self-delivery of active monomers

Proteins and peptides have been used as drugs for almost a century. Technological advances in the past 30 years have enabled the production of pure, stable proteins in vast amounts. In contrast, administration of proteins based on their native active conformation (and thus necessitating the use of s...

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Detalles Bibliográficos
Autores principales: Dekel, Yaron, Machluf, Yossy, Gefen, Tal, Eidelshtein, Gennady, Kotlyar, Alexander, Bram, Yaron, Shahar, Ehud, Reslane, Farah, Aizenshtein, Elina, Pitcovski, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241139/
https://www.ncbi.nlm.nih.gov/pubmed/28156181
http://dx.doi.org/10.1080/10717544.2016.1242179