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Enhancing both oral bioavailability and brain penetration of puerarin using borneol in combination with preparation technologies
Now there are few good oral preparations of puerarin used in cerebrovascular diseases because of its poor oral absorption caused by the low water solubility and the poor penetration into brain. In this study, three oral formulations of puerarin, nanocrystals suspension (NCS), inclusion compounds sol...
Autores principales: | Yi, Tao, Tang, Dandan, Wang, Fan, Zhang, Jiqiong, Zhang, Jiao, Wang, Jirui, Xu, Xiaoyu, Zhang, Jifen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241152/ https://www.ncbi.nlm.nih.gov/pubmed/28165806 http://dx.doi.org/10.1080/10717544.2016.1259372 |
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