Effective intraperitoneal gene transfection system using nanobubbles and ultrasound irradiation

In this study, we demonstrate the low toxicity and highly efficient and spatially improved transfection of plasmid DNA (pDNA) with liposomal nanobubbles (bubble liposomes [BLs]) using ultrasound (US) irradiation in mice. Naked pDNA with BLs was intraperitoneally injected, followed by US irradiation....

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Detalles Bibliográficos
Autores principales: Nishimura, Koyo, Fumoto, Shintaro, Fuchigami, Yuki, Hagimori, Masayori, Maruyama, Kazuo, Kawakami, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241157/
https://www.ncbi.nlm.nih.gov/pubmed/28446052
http://dx.doi.org/10.1080/10717544.2017.1319433

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