Enhanced oral bioavailability and anticancer efficacy of fisetin by encapsulating as inclusion complex with HPβCD in polymeric nanoparticles

Fisetin (FST), a potent anticancer phytoconstituent, exhibits poor aqueous solubility and hence poor bioavailability. The aim of the present study is to improve the oral bioavailability of FST by encapsulating into PLGA NPs (poly-lactide-co-glycolic acid nanoparticles) as a complex of HPβCD (hydroxy...

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Detalles Bibliográficos
Autores principales: Kadari, Amrita, Gudem, Sagarika, Kulhari, Hitesh, Bhandi, Murali Mohan, Borkar, Roshan M., Kolapalli, Venkata Ramana Murthy, Sistla, Ramakrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241160/
https://www.ncbi.nlm.nih.gov/pubmed/28156161
http://dx.doi.org/10.1080/10717544.2016.1245366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241160/
https://www.ncbi.nlm.nih.gov/pubmed/28156161
http://dx.doi.org/10.1080/10717544.2016.1245366

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