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In vitro and in vivo evaluation of macromolecular prodrug GC-FUA based nanoparticle for hepatocellular carcinoma chemotherapy

A novel type of macromolecular prodrug delivery system is reported in this research. The N-galactosylated-chitosan-5-fluorouracil acetic acid conjugate (GC-FUA) based nanoparticle delivery system was evaluated in vitro and in vivo. Biocompatibility of GC-FUA-NPs was screened by BSA adsorption test a...

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Detalles Bibliográficos
Autores principales:	Huang, Can, Li, Na-Mei, Gao, Pei, Yang, Sa, Ning, Qian, Huang, Wen, Li, Zhi-Ping, Ye, Peng-Ju, Xiang, Li, He, Dong-Xiu, Tan, Xiang-Wen, Yu, Cui-Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241166/ https://www.ncbi.nlm.nih.gov/pubmed/28219253 http://dx.doi.org/10.1080/10717544.2016.1264499

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