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Preparation and evaluation of Vinpocetine self-emulsifying pH gradient release pellets
The main objective of this study was to develop a pH gradient release pellet with self-emulsifying drug delivery system (SEDDS), which could not only improve the oral bioavailability of Vinpocetine (VIN), a poor soluble drug, but reduce the fluctuation of plasma concentration. First, the liquid VIN...
Autores principales: | Liu, Mengqi, Zhang, Shiming, Cui, Shuxia, Chen, Fen, Jia, Lianqun, Wang, Shu, Gai, Xiumei, Li, Pingfei, Yang, Feifei, Pan, Weisan, Yang, Xinggang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241196/ https://www.ncbi.nlm.nih.gov/pubmed/29043863 http://dx.doi.org/10.1080/10717544.2017.1388453 |
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