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Dose measurements in a thorax phantom at 3DCRT breast radiation therapy

BACKGROUND: The anthropomorphic and anthropometric phantom developed by the research group NRI (Núcleo de Radiações Ionizantes) can reproduce the effects of the interactions of radiation occurring in the human body. The whole internal radiation transport phenomena can be depicted by film dosimeters...

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Autores principales: Pimenta, Elsa Bifano, Nogueira, Luciana Batista, de Campos, Tarcísio Passos Ribeiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Via Medica 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241292/
https://www.ncbi.nlm.nih.gov/pubmed/34211775
http://dx.doi.org/10.5603/RPOR.a2021.0037
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author Pimenta, Elsa Bifano
Nogueira, Luciana Batista
de Campos, Tarcísio Passos Ribeiro
author_facet Pimenta, Elsa Bifano
Nogueira, Luciana Batista
de Campos, Tarcísio Passos Ribeiro
author_sort Pimenta, Elsa Bifano
collection PubMed
description BACKGROUND: The anthropomorphic and anthropometric phantom developed by the research group NRI (Núcleo de Radiações Ionizantes) can reproduce the effects of the interactions of radiation occurring in the human body. The whole internal radiation transport phenomena can be depicted by film dosimeters in breast RT. Our goal was to provide a dosimetric comparison of a radiation therapy (RT) plan in a 4MV 3D-conformal RT (4MV-3DCR T) and experimental data measured in a breast phantom. MATERIALS AND METHODS: The RT modality was two parallel opposing fields for the left breast with a prescribed dose of 2.0 Gy in 25 fractions. The therapy planning system (TPS) was performed on CA T3D software. The dose readings at points of interest (POI) pre-established in TPS were recorded. An anthropometric thorax-phantom with removal breast was used. EBT2 radiochromic films were inserted into the ipisilateral breast, contralateral breast, lungs, heart and skin. The irradiation was carried out on 4/80 Varian linear accelerator at 4MV. RESULTS: The mean dose at the OAR’s presented statistically significant differences (p < 0.001) of 34.24%, 37.96% and 63.47% for ipsilateral lung, contralateral lung, and heart, respectively. The films placed at the skin-surface interface in the ipsilateral breast also showed statistically significant differences (p < 0.001) of 16.43%, −10.16%, −14.79% and 15.67% in the four quadrants, respectively. In contrast, the PTV dosimeters, representative of the left breast volume, encompassed by the electronic equilibrium, presented a non-significant difference with TPS, p = 0.20 and p = 0.90. CONCLUSION: There was a non-significant difference of doses in PTV with electronic equilibrium; although no match is achieved outside electronic equilibrium.
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spelling pubmed-82412922021-06-30 Dose measurements in a thorax phantom at 3DCRT breast radiation therapy Pimenta, Elsa Bifano Nogueira, Luciana Batista de Campos, Tarcísio Passos Ribeiro Rep Pract Oncol Radiother Research Paper BACKGROUND: The anthropomorphic and anthropometric phantom developed by the research group NRI (Núcleo de Radiações Ionizantes) can reproduce the effects of the interactions of radiation occurring in the human body. The whole internal radiation transport phenomena can be depicted by film dosimeters in breast RT. Our goal was to provide a dosimetric comparison of a radiation therapy (RT) plan in a 4MV 3D-conformal RT (4MV-3DCR T) and experimental data measured in a breast phantom. MATERIALS AND METHODS: The RT modality was two parallel opposing fields for the left breast with a prescribed dose of 2.0 Gy in 25 fractions. The therapy planning system (TPS) was performed on CA T3D software. The dose readings at points of interest (POI) pre-established in TPS were recorded. An anthropometric thorax-phantom with removal breast was used. EBT2 radiochromic films were inserted into the ipisilateral breast, contralateral breast, lungs, heart and skin. The irradiation was carried out on 4/80 Varian linear accelerator at 4MV. RESULTS: The mean dose at the OAR’s presented statistically significant differences (p < 0.001) of 34.24%, 37.96% and 63.47% for ipsilateral lung, contralateral lung, and heart, respectively. The films placed at the skin-surface interface in the ipsilateral breast also showed statistically significant differences (p < 0.001) of 16.43%, −10.16%, −14.79% and 15.67% in the four quadrants, respectively. In contrast, the PTV dosimeters, representative of the left breast volume, encompassed by the electronic equilibrium, presented a non-significant difference with TPS, p = 0.20 and p = 0.90. CONCLUSION: There was a non-significant difference of doses in PTV with electronic equilibrium; although no match is achieved outside electronic equilibrium. Via Medica 2021-04-14 /pmc/articles/PMC8241292/ /pubmed/34211775 http://dx.doi.org/10.5603/RPOR.a2021.0037 Text en © 2021 Greater Poland Cancer Centre https://creativecommons.org/licenses/by-nc-nd/4.0/This article is available in open access under Creative Common Attribution-Non-Commercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0) license, allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially
spellingShingle Research Paper
Pimenta, Elsa Bifano
Nogueira, Luciana Batista
de Campos, Tarcísio Passos Ribeiro
Dose measurements in a thorax phantom at 3DCRT breast radiation therapy
title Dose measurements in a thorax phantom at 3DCRT breast radiation therapy
title_full Dose measurements in a thorax phantom at 3DCRT breast radiation therapy
title_fullStr Dose measurements in a thorax phantom at 3DCRT breast radiation therapy
title_full_unstemmed Dose measurements in a thorax phantom at 3DCRT breast radiation therapy
title_short Dose measurements in a thorax phantom at 3DCRT breast radiation therapy
title_sort dose measurements in a thorax phantom at 3dcrt breast radiation therapy
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241292/
https://www.ncbi.nlm.nih.gov/pubmed/34211775
http://dx.doi.org/10.5603/RPOR.a2021.0037
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