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COVID-19 and the Response of Transplant Centers: the Global Response with an Emphasis on the Kidney Recipient

PURPOSE OF THE REVIEW: In response to the COVID-19 pandemic, vulnerable populations, such as transplant patients, were at greater risk than the regular population. In order to protect these populations, transplant centers enacted new guidelines. We approach this review by looking at how different tr...

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Detalles Bibliográficos
Autores principales: Azzi, Yorg, Brooks, Abigail, Yaffe, Hillary, Greenstein, Stuart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241407/
https://www.ncbi.nlm.nih.gov/pubmed/34221847
http://dx.doi.org/10.1007/s40472-021-00330-5
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author Azzi, Yorg
Brooks, Abigail
Yaffe, Hillary
Greenstein, Stuart
author_facet Azzi, Yorg
Brooks, Abigail
Yaffe, Hillary
Greenstein, Stuart
author_sort Azzi, Yorg
collection PubMed
description PURPOSE OF THE REVIEW: In response to the COVID-19 pandemic, vulnerable populations, such as transplant patients, were at greater risk than the regular population. In order to protect these populations, transplant centers enacted new guidelines. We approach this review by looking at how different transplant regions responded to COVID-19 and analyze the unifying themes that have proven invaluable in the subsequent waves. RECENT FINDINGS: We noticed that most elective surgeries including living donor transplant operations were suspended in most countries. The response to deceased donor transplants varied between countries: in some deceased donor transplants continued with modified donor and recipient criteria, while in other countries this surgery was suspended. There was a general trend of decreasing or holding antimetabolites, treating the virus with hydroxychloroquine and/or azithromycin, and converting outpatient clinics to virtual clinics. SUMMARY: We learned how to carefully select donors and recipients, tailor immunosuppressant regiments, and implement telemedicine. The kidney recipient population can be effectively managed in times of crisis with appropriate accommodations and measures. This review can be a model for the transplant community for future pandemics.
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spelling pubmed-82414072021-06-29 COVID-19 and the Response of Transplant Centers: the Global Response with an Emphasis on the Kidney Recipient Azzi, Yorg Brooks, Abigail Yaffe, Hillary Greenstein, Stuart Curr Transplant Rep Kidney Transplantation (ML Henry and R Pelletier, Section Editors) PURPOSE OF THE REVIEW: In response to the COVID-19 pandemic, vulnerable populations, such as transplant patients, were at greater risk than the regular population. In order to protect these populations, transplant centers enacted new guidelines. We approach this review by looking at how different transplant regions responded to COVID-19 and analyze the unifying themes that have proven invaluable in the subsequent waves. RECENT FINDINGS: We noticed that most elective surgeries including living donor transplant operations were suspended in most countries. The response to deceased donor transplants varied between countries: in some deceased donor transplants continued with modified donor and recipient criteria, while in other countries this surgery was suspended. There was a general trend of decreasing or holding antimetabolites, treating the virus with hydroxychloroquine and/or azithromycin, and converting outpatient clinics to virtual clinics. SUMMARY: We learned how to carefully select donors and recipients, tailor immunosuppressant regiments, and implement telemedicine. The kidney recipient population can be effectively managed in times of crisis with appropriate accommodations and measures. This review can be a model for the transplant community for future pandemics. Springer International Publishing 2021-06-29 2021 /pmc/articles/PMC8241407/ /pubmed/34221847 http://dx.doi.org/10.1007/s40472-021-00330-5 Text en © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Kidney Transplantation (ML Henry and R Pelletier, Section Editors)
Azzi, Yorg
Brooks, Abigail
Yaffe, Hillary
Greenstein, Stuart
COVID-19 and the Response of Transplant Centers: the Global Response with an Emphasis on the Kidney Recipient
title COVID-19 and the Response of Transplant Centers: the Global Response with an Emphasis on the Kidney Recipient
title_full COVID-19 and the Response of Transplant Centers: the Global Response with an Emphasis on the Kidney Recipient
title_fullStr COVID-19 and the Response of Transplant Centers: the Global Response with an Emphasis on the Kidney Recipient
title_full_unstemmed COVID-19 and the Response of Transplant Centers: the Global Response with an Emphasis on the Kidney Recipient
title_short COVID-19 and the Response of Transplant Centers: the Global Response with an Emphasis on the Kidney Recipient
title_sort covid-19 and the response of transplant centers: the global response with an emphasis on the kidney recipient
topic Kidney Transplantation (ML Henry and R Pelletier, Section Editors)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241407/
https://www.ncbi.nlm.nih.gov/pubmed/34221847
http://dx.doi.org/10.1007/s40472-021-00330-5
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