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Developing a multivariate prediction model of antibody features associated with protection of malaria-infected pregnant women from placental malaria

BACKGROUND: Plasmodium falciparum causes placental malaria, which results in adverse outcomes for mother and child. P. falciparum-infected erythrocytes that express the parasite protein VAR2CSA on their surface can bind to placental chondroitin sulfate A. It has been hypothesized that naturally acqu...

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Detalles Bibliográficos
Autores principales: Aitken, Elizabeth H, Damelang, Timon, Ortega-Pajares, Amaya, Alemu, Agersew, Hasang, Wina, Dini, Saber, Unger, Holger W, Ome-Kaius, Maria, Nielsen, Morten A, Salanti, Ali, Smith, Joe, Kent, Stephen, Hogarth, P Mark, Wines, Bruce D, Simpson, Julie A, Chung, Amy W, Rogerson, Stephen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241440/
https://www.ncbi.nlm.nih.gov/pubmed/34181872
http://dx.doi.org/10.7554/eLife.65776