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Famotidine inhibits toll-like receptor 3-mediated inflammatory signaling in SARS-CoV-2 infection
Apart from prevention using vaccinations, the management options for COVID-19 remain limited. In retrospective cohort studies, use of famotidine, a specific oral H2 receptor antagonist (antihistamine), has been associated with reduced risk of intubation and death in patients hospitalized with COVID-...
Autores principales: | Mukherjee, Rukmini, Bhattacharya, Anshu, Bojkova, Denisa, Mehdipour, Ahmad Reza, Shin, Donghyuk, Khan, Khadija Shahed, Hei-Yin Cheung, Hayley, Wong, Kam-Bo, Ng, Wai-Lung, Cinatl, Jindrich, Geurink, Paul P., van der Heden van Noort, Gerbrand J., Rajalingam, Krishnaraj, Ciesek, Sandra, Hummer, Gerhard, Dikic, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241579/ https://www.ncbi.nlm.nih.gov/pubmed/34214498 http://dx.doi.org/10.1016/j.jbc.2021.100925 |
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