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Analysis of RAS gene mutations in cytogenetically normal de novo acute myeloid leukemia patients reveals some novel alterations

Rat sarcoma gene (RAS) holds great importance in pathogenesis of acute myeloid leukemia (AML). The activated mutations in Neuroblastoma rat sarcoma viral oncogene homolog (NRAS) and Kirsten rat sarcoma viral oncogene homolog (KRAS) confers proliferative and survival signals, deliberating numerous ef...

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Detalles Bibliográficos
Autores principales:	Akram, Afia Muhammad, Chaudhary, Asma, Kausar, Humera, Althobaiti, Fayez, Abbas, Afshan Syed, Hussain, Zawar, Fatima, Naz, Zafar, Erum, Asif, Wajiha, Afzal, Umair, Yousaf, Zoufishan, Zafar, Amjad, Harakeh, Steve M., Qamer, Samina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241590/ https://www.ncbi.nlm.nih.gov/pubmed/34220225 http://dx.doi.org/10.1016/j.sjbs.2021.04.089

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