Perampanel, a potent AMPA receptor antagonist, protects against tetramethylenedisulfotetramine-induced seizures and lethality in mice: comparison with diazepam

Tetramethylenedisulfotetramine (TETS), a noncompetitive GABA(A) receptor antagonist, is a potent, highly lethal convulsant that is considered to be a chemical threat agent. Here, we assessed the ability of the AMPA receptor antagonist perampanel to protect against TETS-induced seizures and lethality...

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Detalles Bibliográficos
Autores principales: Zolkowska, Dorota, Dhir, Ashish, Rogawski, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Organ Toxicity and Mechanisms
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241714/
https://www.ncbi.nlm.nih.gov/pubmed/33914090
http://dx.doi.org/10.1007/s00204-021-03053-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241714/
https://www.ncbi.nlm.nih.gov/pubmed/33914090
http://dx.doi.org/10.1007/s00204-021-03053-9

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