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Disruption of myofibroblastic Notch signaling attenuates liver fibrosis by modulating fibrosis progression and regression
The phenotypic transformation of hepatic myofibroblasts (MFs) is involved in the whole process of the progression and regression of liver fibrosis. Notch signaling has been demonstrated to modulate the fibrosis. In this study, we found that Notch signaling in MFs was overactivated and suppressed wit...
Autores principales: | Yue, Zhensheng, Jiang, Zijian, Ruan, Bai, Duan, Juanli, Song, Ping, Liu, Jingjing, Han, Hua, Wang, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241719/ https://www.ncbi.nlm.nih.gov/pubmed/34239344 http://dx.doi.org/10.7150/ijbs.60056 |
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