Targeted therapy for intervertebral disc degeneration: inhibiting apoptosis is a promising treatment strategy

Intervertebral disc (IVD) degeneration (IDD) is a multifactorial pathological process associated with low back pain (LBP). The pathogenesis is complicated, and the main pathological changes are IVD cell apoptosis and extracellular matrix (ECM) degradation. Apoptotic cell loss leads to ECM degradatio...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-bo, Hu, Yi-cun, Cheng, Peng, Zhou, Hai-yu, Chen, Xiang-yi, Wu, Ding, Zhang, Rui-hao, Yu, De-chen, Gao, Xi-dan, Shi, Jin-tao, Zhang, Kai, Li, Shao-long, Song, Peng-jie, Wang, Ke-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241771/
https://www.ncbi.nlm.nih.gov/pubmed/34220308
http://dx.doi.org/10.7150/ijms.59171

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