Cystine reduces tight junction permeability and intestinal inflammation induced by oxidative stress in Caco-2 cells

Intestinal oxidative stress produces pro-inflammatory cytokines, which increase tight junction (TJ) permeability, leading to intestinal and systemic inflammation. Cystine (Cys2) is a substrate of glutathione (GSH) and inhibits inflammation, however, it is unclear whether Cys2 locally improves intest...

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Detalles Bibliográficos
Autores principales: Hasegawa, Tatsuya, Mizugaki, Ami, Inoue, Yoshiko, Kato, Hiroyuki, Murakami, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241805/
https://www.ncbi.nlm.nih.gov/pubmed/33991253
http://dx.doi.org/10.1007/s00726-021-03001-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241805/
https://www.ncbi.nlm.nih.gov/pubmed/33991253
http://dx.doi.org/10.1007/s00726-021-03001-y

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