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Cystine reduces tight junction permeability and intestinal inflammation induced by oxidative stress in Caco-2 cells

Intestinal oxidative stress produces pro-inflammatory cytokines, which increase tight junction (TJ) permeability, leading to intestinal and systemic inflammation. Cystine (Cys2) is a substrate of glutathione (GSH) and inhibits inflammation, however, it is unclear whether Cys2 locally improves intest...

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Detalles Bibliográficos
Autores principales:	Hasegawa, Tatsuya, Mizugaki, Ami, Inoue, Yoshiko, Kato, Hiroyuki, Murakami, Hitoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Vienna 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241805/ https://www.ncbi.nlm.nih.gov/pubmed/33991253 http://dx.doi.org/10.1007/s00726-021-03001-y

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