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The recombinant plant Bauhinia bauhinioides elastase inhibitor reduces rat thrombus without alterations in hemostatic parameters
The anti-inflammatory effects of the plant protease inhibitor BbCI (Bauhinia bauhinioides cruzipain inhibitor), which blocks elastase, cathepsin G, and L, and proteinase 3 has been demonstrated. Here, we investigated the recombinant rBbCI-His((6)) (containing a histidine tail) in an experimental ven...
Autores principales: | Oliveira, Cleide, Valois, Mayara Vioto, Ottaiano, Tatiana Fontes, Miranda, Antonio, Hansen, Daiane, Sampaio, Misako Uemura, Oliva, Maria Luiza Vilela, de Abreu Maffei, Francisco Humberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241853/ https://www.ncbi.nlm.nih.gov/pubmed/34188079 http://dx.doi.org/10.1038/s41598-021-92745-4 |
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