Cargando…
NOTCH-ing up nucleotide metabolism in T-cell acute lymphoblastic leukemia
In a recent issue of Science Advances, Srivastava et al. report a novel nucleotide biosynthesis regulatory role for UBR7 in NOTCH1-driven T-ALL. Here we will discuss their key findings and the implications for using cancer metabolism to understand the development and progression of T-ALL.
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241981/ https://www.ncbi.nlm.nih.gov/pubmed/34188174 http://dx.doi.org/10.1038/s42003-021-02330-8 |