Cargando…

NOD: a web server to predict New use of Old Drugs to facilitate drug repurposing

Computational methods accelerate the drug repurposing pipelines that are a quicker and cost-effective alternative to discovering new molecules. However, there is a paucity of web servers to conduct fast, focussed, and customized investigations for identifying new uses of old drugs. We present the NO...

Descripción completa

Detalles Bibliográficos
Autores principales:	Narwani, Tarun Jairaj, Srinivasan, Narayanaswamy, Chakraborti, Sohini
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241987/ https://www.ncbi.nlm.nih.gov/pubmed/34188160 http://dx.doi.org/10.1038/s41598-021-92903-8

Ejemplares similares

ChemBioServer 2.0: an advanced web server for filtering, clustering and networking of chemical compounds facilitating both drug discovery and repurposing
por: Karatzas, Evangelos, et al.
Publicado: (2020)

DrugRep: an automatic virtual screening server for drug repurposing
por: Gan, Jian-hong, et al.
Publicado: (2022)

‘All That Glitters Is Not Gold’: High-Resolution Crystal Structures of Ligand-Protein Complexes Need Not Always Represent Confident Binding Poses
por: Chakraborti, Sohini, et al.
Publicado: (2021)

PockDrug-Server: a new web server for predicting pocket druggability on holo and apo proteins
por: Hussein, Hiba Abi, et al.
Publicado: (2015)

Auranofin: Repurposing an Old Drug for a Golden New Age
por: Roder, Christine, et al.
Publicado: (2015)

Identification of Potential Binders of Mtb Universal Stress Protein (Rv1636) Through an in silico Approach and Insights Into Compound Selection for Experimental Validation
por: Chakraborti, Sohini, et al.
Publicado: (2021)

Editorial: Flexibility in the genome and proteome: an adaptive toolkit for organisms
por: Narwani, Tarun Jairaj, et al.
Publicado: (2023)

Repurposing old drugs as antiviral agents for coronaviruses
por: Yang, Cheng-Wei, et al.
Publicado: (2020)

Virtual screening on the web for drug repurposing: a primer
por: Chen, Yu Wai, et al.
Publicado: (2021)

Repurposing metformin: an old drug with new tricks in its binding pockets
por: Pryor, Rosina, et al.
Publicado: (2015)

Drug repurposing for breast cancer therapy: Old weapon for new battle
por: Aggarwal, Sadhna, et al.
Publicado: (2021)

iGPCR-Drug: A Web Server for Predicting Interaction between GPCRs and Drugs in Cellular Networking
por: Xiao, Xuan, et al.
Publicado: (2013)

DrugWAS: Leveraging drug-wide association studies to facilitate drug repurposing for COVID-19
por: Bejan, Cosmin A., et al.
Publicado: (2021)

Drug design and repurposing with DockThor-VS web server focusing on SARS-CoV-2 therapeutic targets and their non-synonym variants
por: Guedes, Isabella A., et al.
Publicado: (2021)

From old to new — Repurposing drugs to target mitochondrial energy metabolism in cancer
por: Aminzadeh-Gohari, Sepideh, et al.
Publicado: (2020)

Repurposing Old Drugs into New Epigenetic Inhibitors: Promising Candidates for Cancer Treatment?
por: Moreira-Silva, Filipa, et al.
Publicado: (2020)

Structural Space of the Duffy Antigen/Receptor for Chemokines’ Intrinsically Disordered Ectodomain 1 Explored by Temperature Replica-Exchange Molecular Dynamics Simulations
por: Kranjc, Agata, et al.
Publicado: (2023)

CLAP: A web-server for automatic classification of proteins with special reference to multi-domain proteins
por: Gnanavel, Mutharasu, et al.
Publicado: (2014)

ACFIS: a web server for fragment-based drug discovery
por: Hao, Ge-Fei, et al.
Publicado: (2016)

Integrating heterogeneous data to facilitate COVID-19 drug repurposing
por: Prieto Santamaría, Lucía, et al.
Publicado: (2022)

Data set of intrinsically disordered proteins analysed at a local protein conformation level
por: Melarkode Vattekatte, Akhila, et al.
Publicado: (2020)

Repurposing drugs for highly prevalent diseases: pentoxifylline, an old drug and a new opportunity for diabetic kidney disease
por: Donate-Correa, Javier, et al.
Publicado: (2022)

Sun web server: the essential guide
por: Nelson, Bill, et al.
Publicado: (2009)

Old Weapon for New Enemy: Drug Repurposing for Treatment of Newly Emerging Viral Diseases
por: Guo, Deyin
Publicado: (2020)

Drug Repurposing in Non-Small Cell Lung Carcinoma: Old Solutions for New Problems
por: Doumat, George, et al.
Publicado: (2023)

Pergola-web: a web server for the visualization and analysis of longitudinal behavioral data using repurposed genomics tools and standards
por: Espinosa-Carrasco, Jose, et al.
Publicado: (2019)

Drug ReposER: a web server for predicting similar amino acid arrangements to known drug binding interfaces for potential drug repositioning
por: Ab Ghani, Nur Syatila, et al.
Publicado: (2019)

In silico analysis of Glanzmann variants of Calf-1 domain of α(IIb)β(3) integrin revealed dynamic allosteric effect
por: Goguet, Matthieu, et al.
Publicado: (2017)

Drug repurposing: a systematic review on root causes, barriers and facilitators
por: Krishnamurthy, Nithya, et al.
Publicado: (2022)

Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing
por: Kim, Jong H., et al.
Publicado: (2022)

Virtual screening, ADME/Tox predictions and the drug repurposing concept for future use of old drugs against the COVID-19
por: Hage-Melim, Lorane Izabel da Silva, et al.
Publicado: (2020)

MISA-web: a web server for microsatellite prediction
por: Beier, Sebastian, et al.
Publicado: (2017)

PharmMapper server: a web server for potential drug target identification using pharmacophore mapping approach
por: Liu, Xiaofeng, et al.
Publicado: (2010)

iEzy-Drug: A Web Server for Identifying the Interaction between Enzymes and Drugs in Cellular Networking
por: Min, Jian-Liang, et al.
Publicado: (2013)

CaNDis: a web server for investigation of causal relationships between diseases, drugs and drug targets
por: Škrlj, Blaž, et al.
Publicado: (2020)

Repurposing an ‘Old’ Drug for the Treatment of COVID-19-Related Cytokine Storm
por: Pontali, Emanuele, et al.
Publicado: (2023)

Galahad: a web server for drug effect analysis from gene expression
por: Laenen, Griet, et al.
Publicado: (2015)

Virtual screening web servers: designing chemical probes and drug candidates in the cyberspace
por: Singh, Natesh, et al.
Publicado: (2020)

Editorial: Drug Repurposing
por: Pantziarka, Pan, et al.
Publicado: (2019)

Antifungal Drug Repurposing
por: Kim, Jong H., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_402vqma12u5od5sjbfoir76ksp