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Radiation dosimetry effect evaluation of a carbon fiber couch on novel uRT-linac 506c accelerator

Recently, a diagnostic helical CT is integrated into a linear accelerator, called uRT-linac 506c, whose CT scanning dataset can be directly used to do simulation. This novel structure provides a possibility for online adaptive radiotherapy. For adaptive radiotherapy, the carbon fiber couch is an ess...

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Autores principales: Jiang, Dazhen, Cao, Zhen, Wei, Yongchang, Cao, Tingting, Shen, Jiuling, Xie, Conghua, Zhou, Yunfeng, Liu, Hui, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242010/
https://www.ncbi.nlm.nih.gov/pubmed/34188139
http://dx.doi.org/10.1038/s41598-021-92836-2
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author Jiang, Dazhen
Cao, Zhen
Wei, Yongchang
Cao, Tingting
Shen, Jiuling
Xie, Conghua
Zhou, Yunfeng
Liu, Hui
Zhang, Jun
author_facet Jiang, Dazhen
Cao, Zhen
Wei, Yongchang
Cao, Tingting
Shen, Jiuling
Xie, Conghua
Zhou, Yunfeng
Liu, Hui
Zhang, Jun
author_sort Jiang, Dazhen
collection PubMed
description Recently, a diagnostic helical CT is integrated into a linear accelerator, called uRT-linac 506c, whose CT scanning dataset can be directly used to do simulation. This novel structure provides a possibility for online adaptive radiotherapy. For adaptive radiotherapy, the carbon fiber couch is an essential external device for supporting and positioning patients. And the effect on dose attenuation and distribution caused by a couch is inevitable and vital for precise treatment. In this research, the couch equipped with uRT-linac 506c was evaluated on the radiation dosimetry effect. The treatment couch equipped on the uRT-linac 506c accelerator was evaluated, and its effect on the attenuation, surface dose and dose buildup were measured for different phantom positions (offset = 0 cm, offset =  + 10 cm and offset =  − 10 cm, respectively) and different gantry angles. Since uRT-linac 506c is exclusively capable to provide diagnostic CT scanning data with real relative electron density (RED), this CT scanning data of the couch can be used directly in uRT-TPS to design plans. This scanned couch dataset was designated as the model A. The model B was a dummy structure of a treatment couch inserted with artificially preset RED. The dose calculation accuracy of these two models was compared using PB, CC, and MC on uRT-TPS. With the effect of carbon fiber couch, the surface dose was increased at least 97.94% for 25 × 25 cm(2) field and 188.83% for 10 × 10 cm(2) field, compared with those without. At different phantom positions (offset = 0, + 10, − 10 cm), the attenuation for 6 MV photon beam at gantry angle 180° were 4.4%, 4.4%, and 4.3%, respectively, and varied with changes of gantry angle. There do exists dose deviation between measurement and TPS calculation with the involvement of treatment couch, among the three algorithms, MC presented the least deviation, and the model A made less and steadier deviation than the model B, showing promising superiority. The attenuation, surface dose, and buildup effects of the carbon fiber couch in this study were measured similarly to most counterparts. The dose deviation calculated based on the couch dataset scanned by the diagnostic helical CT was smaller than those based on a dummy couch. This result suggests that an accelerator equipped with a diagnostic CT, which can help reduce the dose deviation of the carbon fiber couch, is a promising platform for online adaptive radiotherapy.
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spelling pubmed-82420102021-07-06 Radiation dosimetry effect evaluation of a carbon fiber couch on novel uRT-linac 506c accelerator Jiang, Dazhen Cao, Zhen Wei, Yongchang Cao, Tingting Shen, Jiuling Xie, Conghua Zhou, Yunfeng Liu, Hui Zhang, Jun Sci Rep Article Recently, a diagnostic helical CT is integrated into a linear accelerator, called uRT-linac 506c, whose CT scanning dataset can be directly used to do simulation. This novel structure provides a possibility for online adaptive radiotherapy. For adaptive radiotherapy, the carbon fiber couch is an essential external device for supporting and positioning patients. And the effect on dose attenuation and distribution caused by a couch is inevitable and vital for precise treatment. In this research, the couch equipped with uRT-linac 506c was evaluated on the radiation dosimetry effect. The treatment couch equipped on the uRT-linac 506c accelerator was evaluated, and its effect on the attenuation, surface dose and dose buildup were measured for different phantom positions (offset = 0 cm, offset =  + 10 cm and offset =  − 10 cm, respectively) and different gantry angles. Since uRT-linac 506c is exclusively capable to provide diagnostic CT scanning data with real relative electron density (RED), this CT scanning data of the couch can be used directly in uRT-TPS to design plans. This scanned couch dataset was designated as the model A. The model B was a dummy structure of a treatment couch inserted with artificially preset RED. The dose calculation accuracy of these two models was compared using PB, CC, and MC on uRT-TPS. With the effect of carbon fiber couch, the surface dose was increased at least 97.94% for 25 × 25 cm(2) field and 188.83% for 10 × 10 cm(2) field, compared with those without. At different phantom positions (offset = 0, + 10, − 10 cm), the attenuation for 6 MV photon beam at gantry angle 180° were 4.4%, 4.4%, and 4.3%, respectively, and varied with changes of gantry angle. There do exists dose deviation between measurement and TPS calculation with the involvement of treatment couch, among the three algorithms, MC presented the least deviation, and the model A made less and steadier deviation than the model B, showing promising superiority. The attenuation, surface dose, and buildup effects of the carbon fiber couch in this study were measured similarly to most counterparts. The dose deviation calculated based on the couch dataset scanned by the diagnostic helical CT was smaller than those based on a dummy couch. This result suggests that an accelerator equipped with a diagnostic CT, which can help reduce the dose deviation of the carbon fiber couch, is a promising platform for online adaptive radiotherapy. Nature Publishing Group UK 2021-06-29 /pmc/articles/PMC8242010/ /pubmed/34188139 http://dx.doi.org/10.1038/s41598-021-92836-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Jiang, Dazhen
Cao, Zhen
Wei, Yongchang
Cao, Tingting
Shen, Jiuling
Xie, Conghua
Zhou, Yunfeng
Liu, Hui
Zhang, Jun
Radiation dosimetry effect evaluation of a carbon fiber couch on novel uRT-linac 506c accelerator
title Radiation dosimetry effect evaluation of a carbon fiber couch on novel uRT-linac 506c accelerator
title_full Radiation dosimetry effect evaluation of a carbon fiber couch on novel uRT-linac 506c accelerator
title_fullStr Radiation dosimetry effect evaluation of a carbon fiber couch on novel uRT-linac 506c accelerator
title_full_unstemmed Radiation dosimetry effect evaluation of a carbon fiber couch on novel uRT-linac 506c accelerator
title_short Radiation dosimetry effect evaluation of a carbon fiber couch on novel uRT-linac 506c accelerator
title_sort radiation dosimetry effect evaluation of a carbon fiber couch on novel urt-linac 506c accelerator
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242010/
https://www.ncbi.nlm.nih.gov/pubmed/34188139
http://dx.doi.org/10.1038/s41598-021-92836-2
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