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Non-canonical function of DGCR8 in DNA double-strand break repair signaling and tumor radioresistance

In response to DNA double-strand breaks (DSBs), repair proteins are recruited to the damaged sites. Ubiquitin signaling plays a critical role in coordinating protein recruitment during the DNA damage response. Here, we find that the microRNA biogenesis factor DGCR8 promotes tumor resistance to X-ray...

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Detalles Bibliográficos
Autores principales:	Hang, Qinglei, Zeng, Liyong, Wang, Li, Nie, Litong, Yao, Fan, Teng, Hongqi, Deng, Yalan, Yap, Shannon, Sun, Yutong, Frank, Steven J., Chen, Junjie, Ma, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242032/ https://www.ncbi.nlm.nih.gov/pubmed/34188037 http://dx.doi.org/10.1038/s41467-021-24298-z

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