SOS1 promotes epithelial-mesenchymal transition of Epithelial Ovarian Cancer(EOC) cells through AKT independent NF-κB signaling pathway

We aimed to explore the role and mechanism of SOS1 (Son of sevenless homolog 1) in malignant behaviors of epithelial ovarian cancer (EOC) cells Hey with high metastatic potential. Firstly, compared with Hey-WT (wild type) and Hey-NT (none targeted) cells, Hey-SOS1i cells showed decreased polarities,...

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Detalles Bibliográficos
Autores principales: Cheng, Min, Ye, Xiaolin, Dai, Jiemin, Sun, Feiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242062/
https://www.ncbi.nlm.nih.gov/pubmed/34175715
http://dx.doi.org/10.1016/j.tranon.2021.101160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242062/
https://www.ncbi.nlm.nih.gov/pubmed/34175715
http://dx.doi.org/10.1016/j.tranon.2021.101160

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