A pH-responsive mesoporous silica nanoparticles-based drug delivery system with controlled release of andrographolide for OA treatment

Andrographolide (AG) has favorable anti-inflammatory and antioxidative capacity. However, it has low bioavailability due to high lipophilicity and can be easily cleared by the synovial fluid after intra-articular injection, leading to low therapeutic efficiency in osteoarthritis (OA). Herein, we des...

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Detalles Bibliográficos
Autores principales: He, Mingwei, Qin, Zainen, Liang, Xiaonan, He, Xixi, Zhu, Bikang, Lu, Zhenhui, Wei, Qingjun, Zheng, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242227/
https://www.ncbi.nlm.nih.gov/pubmed/34221446
http://dx.doi.org/10.1093/rb/rbab020

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