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Means, Motive, and Opportunity: Do Non-Islet-Reactive Infiltrating T Cells Contribute to Autoimmunity in Type 1 Diabetes?

In human type 1 diabetes and animal models of the disease, a diverse assortment of immune cells infiltrates the pancreatic islets. CD8(+) T cells are well represented within infiltrates and HLA multimer staining of pancreas sections provides clear evidence that islet epitope reactive T cells are pre...

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Detalles Bibliográficos
Autores principales:	Rodriguez-Calvo, Teresa, Christoffersson, Gustaf, Bender, Christine, von Herrath, Matthias G., Mallone, Roberto, Kent, Sally C., James, Eddie A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242234/ https://www.ncbi.nlm.nih.gov/pubmed/34220832 http://dx.doi.org/10.3389/fimmu.2021.683091

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