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A Comparative Analysis of Coronavirus Nucleocapsid (N) Proteins Reveals the SADS-CoV N Protein Antagonizes IFN-β Production by Inducing Ubiquitination of RIG-I

Coronaviruses (CoVs) are a known global threat, and most recently the ongoing COVID-19 pandemic has claimed more than 2 million human lives. Delays and interference with IFN responses are closely associated with the severity of disease caused by CoV infection. As the most abundant viral protein in i...

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Detalles Bibliográficos
Autores principales: Liu, Yan, Liang, Qi-Zhang, Lu, Wan, Yang, Yong-Le, Chen, Ruiai, Huang, Yao-Wei, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242249/
https://www.ncbi.nlm.nih.gov/pubmed/34220846
http://dx.doi.org/10.3389/fimmu.2021.688758