Cargando…
A Comparative Analysis of Coronavirus Nucleocapsid (N) Proteins Reveals the SADS-CoV N Protein Antagonizes IFN-β Production by Inducing Ubiquitination of RIG-I
Coronaviruses (CoVs) are a known global threat, and most recently the ongoing COVID-19 pandemic has claimed more than 2 million human lives. Delays and interference with IFN responses are closely associated with the severity of disease caused by CoV infection. As the most abundant viral protein in i...
Autores principales: | Liu, Yan, Liang, Qi-Zhang, Lu, Wan, Yang, Yong-Le, Chen, Ruiai, Huang, Yao-Wei, Wang, Bin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242249/ https://www.ncbi.nlm.nih.gov/pubmed/34220846 http://dx.doi.org/10.3389/fimmu.2021.688758 |
Ejemplares similares
-
Porcine deltacoronavirus nucleocapsid protein antagonizes IFN-β production by impairing dsRNA and PACT binding to RIG-I
por: Chen, Jun, et al.
Publicado: (2019) -
SARS-CoV-2 Nucleocapsid Protein Interacts with RIG-I and Represses RIG-Mediated IFN-β Production
por: Chen, Keli, et al.
Publicado: (2020) -
Porcine Deltacoronavirus Nucleocapsid Protein Suppressed IFN-β Production by Interfering Porcine RIG-I dsRNA-Binding and K63-Linked Polyubiquitination
por: Likai, Ji, et al.
Publicado: (2019) -
The nucleocapsid proteins of mouse hepatitis virus and severe acute respiratory syndrome coronavirus share the same IFN-β antagonizing mechanism: attenuation of PACT-mediated RIG-I/MDA5 activation
por: Ding, Zhen, et al.
Publicado: (2017) -
Bovine coronavirus nucleocapsid suppresses IFN-β production by inhibiting RIG-I-like receptors pathway in host cells
por: Xiangbo, Zhang, et al.
Publicado: (2022)