Acquired thrombotic thrombocytopenic purpura with possible association with AstraZeneca‐Oxford COVID‐19 vaccine

Acquired thrombotic thrombocytopenic purpura is characterized by the microvascular aggregation of platelets and microangiopathic hemolytic anemia causing ischemia of multiple organs including the brain mainly and less likely the kidney and the heart. The disease is caused by severe reduction in the...

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Autores principales: Al‐Ahmad, Mona, Al‐Rasheed, Mona, Shalaby, Neveen Abo Bakr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242544/
https://www.ncbi.nlm.nih.gov/pubmed/34226899
http://dx.doi.org/10.1002/jha2.219
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author Al‐Ahmad, Mona
Al‐Rasheed, Mona
Shalaby, Neveen Abo Bakr
author_facet Al‐Ahmad, Mona
Al‐Rasheed, Mona
Shalaby, Neveen Abo Bakr
author_sort Al‐Ahmad, Mona
collection PubMed
description Acquired thrombotic thrombocytopenic purpura is characterized by the microvascular aggregation of platelets and microangiopathic hemolytic anemia causing ischemia of multiple organs including the brain mainly and less likely the kidney and the heart. The disease is caused by severe reduction in the activity of ADAMTS 13 due to presence of inhibitory antibodies.
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spelling pubmed-82425442021-07-01 Acquired thrombotic thrombocytopenic purpura with possible association with AstraZeneca‐Oxford COVID‐19 vaccine Al‐Ahmad, Mona Al‐Rasheed, Mona Shalaby, Neveen Abo Bakr EJHaem Case Reports Acquired thrombotic thrombocytopenic purpura is characterized by the microvascular aggregation of platelets and microangiopathic hemolytic anemia causing ischemia of multiple organs including the brain mainly and less likely the kidney and the heart. The disease is caused by severe reduction in the activity of ADAMTS 13 due to presence of inhibitory antibodies. John Wiley and Sons Inc. 2021-05-18 /pmc/articles/PMC8242544/ /pubmed/34226899 http://dx.doi.org/10.1002/jha2.219 Text en © 2021 The Authors. eJHaem published by British Society for Haematology and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Al‐Ahmad, Mona
Al‐Rasheed, Mona
Shalaby, Neveen Abo Bakr
Acquired thrombotic thrombocytopenic purpura with possible association with AstraZeneca‐Oxford COVID‐19 vaccine
title Acquired thrombotic thrombocytopenic purpura with possible association with AstraZeneca‐Oxford COVID‐19 vaccine
title_full Acquired thrombotic thrombocytopenic purpura with possible association with AstraZeneca‐Oxford COVID‐19 vaccine
title_fullStr Acquired thrombotic thrombocytopenic purpura with possible association with AstraZeneca‐Oxford COVID‐19 vaccine
title_full_unstemmed Acquired thrombotic thrombocytopenic purpura with possible association with AstraZeneca‐Oxford COVID‐19 vaccine
title_short Acquired thrombotic thrombocytopenic purpura with possible association with AstraZeneca‐Oxford COVID‐19 vaccine
title_sort acquired thrombotic thrombocytopenic purpura with possible association with astrazeneca‐oxford covid‐19 vaccine
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242544/
https://www.ncbi.nlm.nih.gov/pubmed/34226899
http://dx.doi.org/10.1002/jha2.219
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AT shalabyneveenabobakr acquiredthromboticthrombocytopenicpurpurawithpossibleassociationwithastrazenecaoxfordcovid19vaccine

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