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Lessons learnt from COVID‐19 coagulopathy

The coronavirus disease 2019 (COVID‐19) pandemic has already left an indelible mark in human lives. Despite the havoc it created, this pandemic also saw significant advances in the management of an infectious disease wherein worldwide collaborative efforts from health care professionals have been un...

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Autor principal: Thachil, Jecko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242569/
https://www.ncbi.nlm.nih.gov/pubmed/34226900
http://dx.doi.org/10.1002/jha2.228
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author Thachil, Jecko
author_facet Thachil, Jecko
author_sort Thachil, Jecko
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description The coronavirus disease 2019 (COVID‐19) pandemic has already left an indelible mark in human lives. Despite the havoc it created, this pandemic also saw significant advances in the management of an infectious disease wherein worldwide collaborative efforts from health care professionals have been unprecedented. One of the commonest complications recognised early in the pandemic is the development of coagulopathy. In this review, the lessons learnt from COVID‐19 coagulopathy are summarised with some perspectives on future clinical and research strategies. These include how local versus systemic coagulopathy can matter, how we can put D‐dimers to effective use, exhort more input into identifying a simple platelet activation marker, rethink the role of fibrinogen, look differently at lupus anticoagulant and heparin‐induced thrombocytopenia, bring back disseminated intravascular coagulation into our differential diagnosis slate and most importantly channel more funding into haemostasis and thrombosis research.
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spelling pubmed-82425692021-07-01 Lessons learnt from COVID‐19 coagulopathy Thachil, Jecko EJHaem Reviews The coronavirus disease 2019 (COVID‐19) pandemic has already left an indelible mark in human lives. Despite the havoc it created, this pandemic also saw significant advances in the management of an infectious disease wherein worldwide collaborative efforts from health care professionals have been unprecedented. One of the commonest complications recognised early in the pandemic is the development of coagulopathy. In this review, the lessons learnt from COVID‐19 coagulopathy are summarised with some perspectives on future clinical and research strategies. These include how local versus systemic coagulopathy can matter, how we can put D‐dimers to effective use, exhort more input into identifying a simple platelet activation marker, rethink the role of fibrinogen, look differently at lupus anticoagulant and heparin‐induced thrombocytopenia, bring back disseminated intravascular coagulation into our differential diagnosis slate and most importantly channel more funding into haemostasis and thrombosis research. John Wiley and Sons Inc. 2021-05-17 /pmc/articles/PMC8242569/ /pubmed/34226900 http://dx.doi.org/10.1002/jha2.228 Text en © 2021 The Authors. eJHaem published by British Society for Haematology and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Thachil, Jecko
Lessons learnt from COVID‐19 coagulopathy
title Lessons learnt from COVID‐19 coagulopathy
title_full Lessons learnt from COVID‐19 coagulopathy
title_fullStr Lessons learnt from COVID‐19 coagulopathy
title_full_unstemmed Lessons learnt from COVID‐19 coagulopathy
title_short Lessons learnt from COVID‐19 coagulopathy
title_sort lessons learnt from covid‐19 coagulopathy
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242569/
https://www.ncbi.nlm.nih.gov/pubmed/34226900
http://dx.doi.org/10.1002/jha2.228
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