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Lessons learnt from COVID‐19 coagulopathy
The coronavirus disease 2019 (COVID‐19) pandemic has already left an indelible mark in human lives. Despite the havoc it created, this pandemic also saw significant advances in the management of an infectious disease wherein worldwide collaborative efforts from health care professionals have been un...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley and Sons Inc.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242569/ https://www.ncbi.nlm.nih.gov/pubmed/34226900 http://dx.doi.org/10.1002/jha2.228 |
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author | Thachil, Jecko |
author_facet | Thachil, Jecko |
author_sort | Thachil, Jecko |
collection | PubMed |
description | The coronavirus disease 2019 (COVID‐19) pandemic has already left an indelible mark in human lives. Despite the havoc it created, this pandemic also saw significant advances in the management of an infectious disease wherein worldwide collaborative efforts from health care professionals have been unprecedented. One of the commonest complications recognised early in the pandemic is the development of coagulopathy. In this review, the lessons learnt from COVID‐19 coagulopathy are summarised with some perspectives on future clinical and research strategies. These include how local versus systemic coagulopathy can matter, how we can put D‐dimers to effective use, exhort more input into identifying a simple platelet activation marker, rethink the role of fibrinogen, look differently at lupus anticoagulant and heparin‐induced thrombocytopenia, bring back disseminated intravascular coagulation into our differential diagnosis slate and most importantly channel more funding into haemostasis and thrombosis research. |
format | Online Article Text |
id | pubmed-8242569 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82425692021-07-01 Lessons learnt from COVID‐19 coagulopathy Thachil, Jecko EJHaem Reviews The coronavirus disease 2019 (COVID‐19) pandemic has already left an indelible mark in human lives. Despite the havoc it created, this pandemic also saw significant advances in the management of an infectious disease wherein worldwide collaborative efforts from health care professionals have been unprecedented. One of the commonest complications recognised early in the pandemic is the development of coagulopathy. In this review, the lessons learnt from COVID‐19 coagulopathy are summarised with some perspectives on future clinical and research strategies. These include how local versus systemic coagulopathy can matter, how we can put D‐dimers to effective use, exhort more input into identifying a simple platelet activation marker, rethink the role of fibrinogen, look differently at lupus anticoagulant and heparin‐induced thrombocytopenia, bring back disseminated intravascular coagulation into our differential diagnosis slate and most importantly channel more funding into haemostasis and thrombosis research. John Wiley and Sons Inc. 2021-05-17 /pmc/articles/PMC8242569/ /pubmed/34226900 http://dx.doi.org/10.1002/jha2.228 Text en © 2021 The Authors. eJHaem published by British Society for Haematology and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Reviews Thachil, Jecko Lessons learnt from COVID‐19 coagulopathy |
title | Lessons learnt from COVID‐19 coagulopathy |
title_full | Lessons learnt from COVID‐19 coagulopathy |
title_fullStr | Lessons learnt from COVID‐19 coagulopathy |
title_full_unstemmed | Lessons learnt from COVID‐19 coagulopathy |
title_short | Lessons learnt from COVID‐19 coagulopathy |
title_sort | lessons learnt from covid‐19 coagulopathy |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242569/ https://www.ncbi.nlm.nih.gov/pubmed/34226900 http://dx.doi.org/10.1002/jha2.228 |
work_keys_str_mv | AT thachiljecko lessonslearntfromcovid19coagulopathy |