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Vascular pattern and radiological follow up in a case of pontine warning syndrome

Pontine warning syndrome (PWS) is a condition characterized by crescendo transient ischemic attacks due to pontine ischemia. The reported case described a 72-year-old woman who presented repetitive sudden episodes of double vision, impaired balance, slurred speech and right-sided weakness. Neurologi...

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Autores principales: Currò, Carmelo Tiberio, Francalanza, Isabella, Cotroneo, Masina, Dell’Aera, Cristina, Casella, Carmela, La Spina, Paolino, Fazio, Maria Carolina, Grillo, Francesco, Toscano, Antonio, Musolino, Rosa Fortunata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242993/
https://www.ncbi.nlm.nih.gov/pubmed/34222700
http://dx.doi.org/10.1016/j.heliyon.2021.e07369
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author Currò, Carmelo Tiberio
Francalanza, Isabella
Cotroneo, Masina
Dell’Aera, Cristina
Casella, Carmela
La Spina, Paolino
Fazio, Maria Carolina
Grillo, Francesco
Toscano, Antonio
Musolino, Rosa Fortunata
author_facet Currò, Carmelo Tiberio
Francalanza, Isabella
Cotroneo, Masina
Dell’Aera, Cristina
Casella, Carmela
La Spina, Paolino
Fazio, Maria Carolina
Grillo, Francesco
Toscano, Antonio
Musolino, Rosa Fortunata
author_sort Currò, Carmelo Tiberio
collection PubMed
description Pontine warning syndrome (PWS) is a condition characterized by crescendo transient ischemic attacks due to pontine ischemia. The reported case described a 72-year-old woman who presented repetitive sudden episodes of double vision, impaired balance, slurred speech and right-sided weakness. Neurological deficits lasted a few minutes-hours and disappeared during the first seven days after onset. On the 1st day, MRI revealed acute left paramedian pontine infarction with focal swelling. Supra-aortic vessel imagining revealed bilateral internal carotid stenosis of 50%; hypoplasia of the left vertebral artery. On the 7th day, MRI showed a tissue swelling reduction, and from that day, she had no symptoms. These clinical and radiological features were suggestive of PWS. Our patient presented a particular vascular pattern that could favour symptoms fluctuation. We performed a close MRI follow up and it allowed us to observe a clinical stabilization in association with edema reduction.
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spelling pubmed-82429932021-07-02 Vascular pattern and radiological follow up in a case of pontine warning syndrome Currò, Carmelo Tiberio Francalanza, Isabella Cotroneo, Masina Dell’Aera, Cristina Casella, Carmela La Spina, Paolino Fazio, Maria Carolina Grillo, Francesco Toscano, Antonio Musolino, Rosa Fortunata Heliyon Case Report Pontine warning syndrome (PWS) is a condition characterized by crescendo transient ischemic attacks due to pontine ischemia. The reported case described a 72-year-old woman who presented repetitive sudden episodes of double vision, impaired balance, slurred speech and right-sided weakness. Neurological deficits lasted a few minutes-hours and disappeared during the first seven days after onset. On the 1st day, MRI revealed acute left paramedian pontine infarction with focal swelling. Supra-aortic vessel imagining revealed bilateral internal carotid stenosis of 50%; hypoplasia of the left vertebral artery. On the 7th day, MRI showed a tissue swelling reduction, and from that day, she had no symptoms. These clinical and radiological features were suggestive of PWS. Our patient presented a particular vascular pattern that could favour symptoms fluctuation. We performed a close MRI follow up and it allowed us to observe a clinical stabilization in association with edema reduction. Elsevier 2021-06-22 /pmc/articles/PMC8242993/ /pubmed/34222700 http://dx.doi.org/10.1016/j.heliyon.2021.e07369 Text en © 2021 Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Currò, Carmelo Tiberio
Francalanza, Isabella
Cotroneo, Masina
Dell’Aera, Cristina
Casella, Carmela
La Spina, Paolino
Fazio, Maria Carolina
Grillo, Francesco
Toscano, Antonio
Musolino, Rosa Fortunata
Vascular pattern and radiological follow up in a case of pontine warning syndrome
title Vascular pattern and radiological follow up in a case of pontine warning syndrome
title_full Vascular pattern and radiological follow up in a case of pontine warning syndrome
title_fullStr Vascular pattern and radiological follow up in a case of pontine warning syndrome
title_full_unstemmed Vascular pattern and radiological follow up in a case of pontine warning syndrome
title_short Vascular pattern and radiological follow up in a case of pontine warning syndrome
title_sort vascular pattern and radiological follow up in a case of pontine warning syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242993/
https://www.ncbi.nlm.nih.gov/pubmed/34222700
http://dx.doi.org/10.1016/j.heliyon.2021.e07369
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