Cargando…

Renal neoplasms in tuberous sclerosis mice are neurocristopathies

Tuberous sclerosis (TS) is a rare disorder exhibiting multi-systemic benign neoplasms. We hypothesized the origin of TS neoplastic cells derived from the neural crest given the heterogeneous ecto-mesenchymal phenotype of the most common TS neoplasms. To test this hypothesis, we employed Cre-loxP lin...

Descripción completa

Detalles Bibliográficos
Autores principales: Unachukwu, Uchenna, Shiomi, Takayuki, Goldklang, Monica, Chada, Kiran, D'Armiento, Jeanine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243016/
https://www.ncbi.nlm.nih.gov/pubmed/34222844
http://dx.doi.org/10.1016/j.isci.2021.102684