Halting targeted and collateral damage to red blood cells by the complement system

The complement system is an important defense mechanism against pathogens; however, in certain pathologies, the system also attacks human cells, such as red blood cells (RBCs). In paroxysmal nocturnal hemoglobinuria (PNH), RBCs lack certain complement regulators which sensitize them to complement-me...

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Detalles Bibliográficos
Autores principales: Jalink, M., de Boer, E. C. W., Evers, D., Havinga, M. Q., Vos, J. M. I., Zeerleder, S., de Haas, M., Jongerius, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243056/
https://www.ncbi.nlm.nih.gov/pubmed/34191092
http://dx.doi.org/10.1007/s00281-021-00859-8

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