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Data-Driven Ensemble Docking to Map Molecular Interactions of Steroid Analogs with Hepatic Organic Anion Transporting Polypeptides

[Image: see text] Hepatic organic anion transporting polypeptides—OATP1B1, OATP1B3, and OATP2B1—are expressed at the basolateral membrane of hepatocytes, being responsible for the uptake of a wide range of natural substrates and structurally unrelated pharmaceuticals. Impaired function of hepatic OA...

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Detalles Bibliográficos
Autores principales:	Tuerkova, Alzbeta, Ungvári, Orsolya, Laczkó-Rigó, Réka, Mernyák, Erzsébet, Szakács, Gergely, Özvegy-Laczka, Csilla, Zdrazil, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243326/ https://www.ncbi.nlm.nih.gov/pubmed/34105971 http://dx.doi.org/10.1021/acs.jcim.1c00362

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