Glucose regulates expression of pro-inflammatory genes, IL-1β and IL-12, through a mechanism involving hexosamine biosynthesis pathway-dependent regulation of α-E catenin

High glucose levels are associated with changes in macrophage polarisation and evidence indicates that the sustained or even short-term high glucose levels modulate inflammatory responses in macrophages. However, the mechanism by which macrophages can sense the changes in glucose levels are not clea...

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Detalles Bibliográficos
Autores principales: Dissanayake, Waruni C., Oh, Jin Kyo, Sorrenson, Brie, Shepherd, Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Signaling
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243339/
https://www.ncbi.nlm.nih.gov/pubmed/34139004
http://dx.doi.org/10.1042/BSR20211066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243339/
https://www.ncbi.nlm.nih.gov/pubmed/34139004
http://dx.doi.org/10.1042/BSR20211066

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