Increased expression of yes-associated protein/YAP and transcriptional coactivator with PDZ-binding motif/TAZ activates intestinal fibroblasts to promote intestinal obstruction in Crohn's disease

BACKGROUND: Intestinal obstruction caused by intestinal fibrosis is a common and serious complication of Crohn's disease (CD). Intestinal fibroblasts, the main effector cells mediating gastrointestinal fibrosis, are activated during chronic inflammation. However, the mechanism of fibroblast act...

Descripción completa

Detalles Bibliográficos
Autores principales: Ou, Weijun, Xu, Weimin, Liu, Fangyuan, Guo, Yuegui, Huang, Zhenyu, Feng, Tienan, Liu, Chen-Ying, Du, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243379/
https://www.ncbi.nlm.nih.gov/pubmed/34186485
http://dx.doi.org/10.1016/j.ebiom.2021.103452

Ejemplares similares

Ejemplares similares