Osteopontin isoform c promotes the survival of cisplatin-treated NSCLC cells involving NFATc2-mediated suppression on calcium-induced ROS levels

BACKGROUND: Tumor microenvironment (TME) critically contributed to the malignant progression of transformed cells and the chemical responses to chemotherapy reagents. Osteopontin (OPN) is a secretory onco-protein with several splicing isoforms, all of which were known to regulate tumor growth and ab...

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Detalles Bibliográficos
Autores principales: Huang, Jing, Hu, Mu, Niu, Huan, Wang, Jing, Si, Yang, Cheng, Shan, Ding, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243455/
https://www.ncbi.nlm.nih.gov/pubmed/34187410
http://dx.doi.org/10.1186/s12885-021-08495-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243455/
https://www.ncbi.nlm.nih.gov/pubmed/34187410
http://dx.doi.org/10.1186/s12885-021-08495-z

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