Double overexpression of miR-19a and miR-20a in induced pluripotent stem cell-derived mesenchymal stem cells effectively preserves the left ventricular function in dilated cardiomyopathic rat

BACKGROUND: This study tested the hypothesis that double overexpression of miR-19a and miR-20a (dOex-mIRs) in human induced pluripotent stem cell (iPS)-derived mesenchymal stem cells (MSCs) effectively preserved left ventricular ejection fraction (LVEF) in dilated cardiomyopathy (DCM) (i.e., induced...

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Detalles Bibliográficos
Autores principales: Sheu, Jiunn-Jye, Chai, Han-Tan, Sung, Pei-Hsun, Chiang, John Y., Huang, Tien-Hung, Shao, Pei-Lin, Wu, Shun-Cheng, Yip, Hon-Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243466/
https://www.ncbi.nlm.nih.gov/pubmed/34187571
http://dx.doi.org/10.1186/s13287-021-02440-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243466/
https://www.ncbi.nlm.nih.gov/pubmed/34187571
http://dx.doi.org/10.1186/s13287-021-02440-4

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