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Double overexpression of miR-19a and miR-20a in induced pluripotent stem cell-derived mesenchymal stem cells effectively preserves the left ventricular function in dilated cardiomyopathic rat
BACKGROUND: This study tested the hypothesis that double overexpression of miR-19a and miR-20a (dOex-mIRs) in human induced pluripotent stem cell (iPS)-derived mesenchymal stem cells (MSCs) effectively preserved left ventricular ejection fraction (LVEF) in dilated cardiomyopathy (DCM) (i.e., induced...
Autores principales: | Sheu, Jiunn-Jye, Chai, Han-Tan, Sung, Pei-Hsun, Chiang, John Y., Huang, Tien-Hung, Shao, Pei-Lin, Wu, Shun-Cheng, Yip, Hon-Kan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243466/ https://www.ncbi.nlm.nih.gov/pubmed/34187571 http://dx.doi.org/10.1186/s13287-021-02440-4 |
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