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Correlation of non-clinical parameters with the hematological indices in type 2 diabetic Mellitus patients

BACKGROUND: The study's main aim is to compare and correlate the levels of various hematological indices in type 2 DM patients with the gender, age, duration, and family history of diabetic conditions to predict diabetes-related complications. METHODS: The diabetic population is divided into 2,...

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Detalles Bibliográficos
Autores principales: Sampathkumar, Vamitha Paneerselvam, Krishnamurthy, Prathipa, Balaraman, Saravanan, Balaiya, Dhivya, Sivaraman, Ravi, Manjunathan, Reji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243508/
https://www.ncbi.nlm.nih.gov/pubmed/34222698
http://dx.doi.org/10.1016/j.heliyon.2021.e07366
Descripción
Sumario:BACKGROUND: The study's main aim is to compare and correlate the levels of various hematological indices in type 2 DM patients with the gender, age, duration, and family history of diabetic conditions to predict diabetes-related complications. METHODS: The diabetic population is divided into 2, group 1- subjects with complications and group 2- subjects without complications. Hematological indices are measured using an automated analyzer. RESULTS: Females from group 1 show a significantly higher value for PLC (3.72 ± 4.79/<0.05) and positively correlate with the diabetic duration. Females with >40 years of age from group 2 show a significantly higher value for platelet larger cell ratio (P-LCR/%) (40.17 ± 3.25 (>40)/<0.05) than those with <40 age and positively correlated with the age. Males with >40 years of age from group 1 show a significantly higher value for plateletcrit (PCT/%) (0.297 ± 0.067 (>40)/<0.05) than those from <40 age and positively correlated with the age. All the male subjects show significant higher values for hemoglobin concentration (HB/g/dl) (13.49 ± 2.22)/<0.05 for group 1) (13.61 ± 2.02)/<0.05 for group 2) and hematocrit (HCT/L/L) (37.30 ± 7.55/<0.05 for group 1) (38.64 ± 5.42/<0.05 for group 2). CONCLUSION: Correlating the hematological indices with the gender, age, and duration of diabetic condition will help determine future complications and the severity of the diabetic condition in type 2 DM patients.