A new high-content screening assay of the entire hepatitis B virus life cycle identifies novel antivirals

BACKGROUND & AIMS: Chronic hepatitis B is an incurable disease. Addressing the unmet medical need for therapies has been hampered by a lack of suitable cell culture models to investigate the HBV life cycle in a single experimental setup. We sought to develop a platform suitable to investigate al...

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Detalles Bibliográficos
Autores principales: Yang, Jaewon, König, Alexander, Park, Soonju, Jo, Eunji, Sung, Pil Soo, Yoon, Seung Kew, Zusinaite, Eva, Kainov, Denis, Shum, David, Windisch, Marc Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243515/
https://www.ncbi.nlm.nih.gov/pubmed/34222850
http://dx.doi.org/10.1016/j.jhepr.2021.100296

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