Presepsin values and prognostic nutritional index predict mortality in intensive care unit patients with sepsis: a pilot study

OBJECTIVE: Sepsis is a major cause of mortality for critically ill patients. This study aimed to determine whether presepsin values can predict mortality in patients with sepsis. RESULTS: Receiver operating characteristic (ROC) curve analysis, Log-rank test, and multivariate analysis identified pres...

Descripción completa

Detalles Bibliográficos
Autores principales: Shimoyama, Yuichiro, Umegaki, Osamu, Kadono, Noriko, Minami, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243529/
https://www.ncbi.nlm.nih.gov/pubmed/34193271
http://dx.doi.org/10.1186/s13104-021-05659-9
Descripción
Sumario:OBJECTIVE: Sepsis is a major cause of mortality for critically ill patients. This study aimed to determine whether presepsin values can predict mortality in patients with sepsis. RESULTS: Receiver operating characteristic (ROC) curve analysis, Log-rank test, and multivariate analysis identified presepsin values and Prognostic Nutritional Index as predictors of mortality in sepsis patients. Presepsin value on Day 1 was a predictor of early mortality, i.e., death within 7 days of ICU admission; ROC curve analysis revealed an AUC of 0.84, sensitivity of 89%, and specificity of 77%; and multivariate analysis showed an OR of 1.0007, with a 95%CI of 1.0001–1.0013 (p = 0.0320). SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13104-021-05659-9.

Ejemplares similares