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SRPK1/AKT axis promotes oxaliplatin-induced anti-apoptosis via NF-κB activation in colon cancer

BACKGROUND: Colorectal cancer is the third most common diagnosis. Oxaliplatin is used as first-line treatment of colon cancer. However, oxaliplatin resistance greatly reduces its therapeutic effect. SRPK1 involves in pre-mRNA splicing and tumorigenesis. How SRPK1 mediates drug resistance in colon ca...

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Detalles Bibliográficos
Autores principales:	Huang, Jing-Qiang, Li, He-Feng, Zhu, Jing, Song, Jun-Wei, Zhang, Xian-Bin, Gong, Peng, Liu, Qiu-Yu, Zhou, Chun-Hui, Wang, Liang, Gong, Li-Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243872/ https://www.ncbi.nlm.nih.gov/pubmed/34193174 http://dx.doi.org/10.1186/s12967-021-02954-8

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