Cargando…
SRPK1/AKT axis promotes oxaliplatin-induced anti-apoptosis via NF-κB activation in colon cancer
BACKGROUND: Colorectal cancer is the third most common diagnosis. Oxaliplatin is used as first-line treatment of colon cancer. However, oxaliplatin resistance greatly reduces its therapeutic effect. SRPK1 involves in pre-mRNA splicing and tumorigenesis. How SRPK1 mediates drug resistance in colon ca...
Autores principales: | Huang, Jing-Qiang, Li, He-Feng, Zhu, Jing, Song, Jun-Wei, Zhang, Xian-Bin, Gong, Peng, Liu, Qiu-Yu, Zhou, Chun-Hui, Wang, Liang, Gong, Li-Yun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243872/ https://www.ncbi.nlm.nih.gov/pubmed/34193174 http://dx.doi.org/10.1186/s12967-021-02954-8 |
Ejemplares similares
-
The many faces of SRPK1
por: Bullock, Nicholas, et al.
Publicado: (2017) -
PEA-OXA Mitigates Oxaliplatin-Induced Painful Neuropathy through NF-κB/Nrf-2 Axis
por: Campolo, Michela, et al.
Publicado: (2021) -
SRPK1/2 and PP1α exert opposite functions by modulating SRSF1-guided MKNK2 alternative splicing in colon adenocarcinoma
por: Liu, Hongda, et al.
Publicado: (2021) -
Elevated SRPK1 lessens apoptosis in breast cancer cells through RBM4-regulated splicing events
por: Lin, Jung-Chun, et al.
Publicado: (2014) -
Paeonol-mediated apoptosis of hepatocellular carcinoma cells by NF-κB pathway
por: Li, Qiang, et al.
Publicado: (2019)