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SAR and temperature distributions in a database of realistic human models for 7 T cardiac imaging

PURPOSE: To investigate inter‐subject variability of B (1) (+), SAR and temperature rise in a database of human models using a local transmit array for 7 T cardiac imaging. METHODS: Dixon images were acquired of 14 subjects and segmented in dielectric models with an eight‐channel local transmit arra...

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Autores principales: Steensma, Bart R., Meliadò, Ettore F., Luijten, Peter, Klomp, Dennis W. J., van den Berg, Cornelis A. T., Raaijmakers, Alexander J. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244032/
https://www.ncbi.nlm.nih.gov/pubmed/33955061
http://dx.doi.org/10.1002/nbm.4525
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author Steensma, Bart R.
Meliadò, Ettore F.
Luijten, Peter
Klomp, Dennis W. J.
van den Berg, Cornelis A. T.
Raaijmakers, Alexander J. E.
author_facet Steensma, Bart R.
Meliadò, Ettore F.
Luijten, Peter
Klomp, Dennis W. J.
van den Berg, Cornelis A. T.
Raaijmakers, Alexander J. E.
author_sort Steensma, Bart R.
collection PubMed
description PURPOSE: To investigate inter‐subject variability of B (1) (+), SAR and temperature rise in a database of human models using a local transmit array for 7 T cardiac imaging. METHODS: Dixon images were acquired of 14 subjects and segmented in dielectric models with an eight‐channel local transmit array positioned around the torso for cardiac imaging. EM simulations were done to calculate SAR distributions. Based on the SAR distributions, temperature simulations were performed for exposure times of 6 min and 30 min. Peak local SAR and temperature rise levels were calculated for different RF shim settings. A statistical analysis of the resulting peak local SAR and temperature rise levels was performed to arrive at safe power limits. RESULTS: For RF shim vectors with random phase and uniformly distributed power, a safe average power limit of 35.7 W was determined (first level controlled mode). When RF amplitude and phase shimming was performed on the heart, a safe average power limit of 35.0 W was found. According to Pennes' model, our numerical study suggests a very low probability of exceeding the absolute local temperature limit of 40 °C for a total exposure time of 6 min and a peak local SAR of 20 W/kg. For a 30 min exposure time at 20 W/kg, it was shown that the absolute temperature limit can be exceeded in the case where perfusion does not change with temperature. CONCLUSION: Safe power constraints were found for 7 T cardiac imaging with an eight‐channel local transmit array, while considering the inter‐subject variability of B (1) (+), SAR and temperature rise.
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spelling pubmed-82440322021-07-02 SAR and temperature distributions in a database of realistic human models for 7 T cardiac imaging Steensma, Bart R. Meliadò, Ettore F. Luijten, Peter Klomp, Dennis W. J. van den Berg, Cornelis A. T. Raaijmakers, Alexander J. E. NMR Biomed Research Articles PURPOSE: To investigate inter‐subject variability of B (1) (+), SAR and temperature rise in a database of human models using a local transmit array for 7 T cardiac imaging. METHODS: Dixon images were acquired of 14 subjects and segmented in dielectric models with an eight‐channel local transmit array positioned around the torso for cardiac imaging. EM simulations were done to calculate SAR distributions. Based on the SAR distributions, temperature simulations were performed for exposure times of 6 min and 30 min. Peak local SAR and temperature rise levels were calculated for different RF shim settings. A statistical analysis of the resulting peak local SAR and temperature rise levels was performed to arrive at safe power limits. RESULTS: For RF shim vectors with random phase and uniformly distributed power, a safe average power limit of 35.7 W was determined (first level controlled mode). When RF amplitude and phase shimming was performed on the heart, a safe average power limit of 35.0 W was found. According to Pennes' model, our numerical study suggests a very low probability of exceeding the absolute local temperature limit of 40 °C for a total exposure time of 6 min and a peak local SAR of 20 W/kg. For a 30 min exposure time at 20 W/kg, it was shown that the absolute temperature limit can be exceeded in the case where perfusion does not change with temperature. CONCLUSION: Safe power constraints were found for 7 T cardiac imaging with an eight‐channel local transmit array, while considering the inter‐subject variability of B (1) (+), SAR and temperature rise. John Wiley and Sons Inc. 2021-05-06 2021-07 /pmc/articles/PMC8244032/ /pubmed/33955061 http://dx.doi.org/10.1002/nbm.4525 Text en © 2021 The Authors. NMR in Biomedicine published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Research Articles
Steensma, Bart R.
Meliadò, Ettore F.
Luijten, Peter
Klomp, Dennis W. J.
van den Berg, Cornelis A. T.
Raaijmakers, Alexander J. E.
SAR and temperature distributions in a database of realistic human models for 7 T cardiac imaging
title SAR and temperature distributions in a database of realistic human models for 7 T cardiac imaging
title_full SAR and temperature distributions in a database of realistic human models for 7 T cardiac imaging
title_fullStr SAR and temperature distributions in a database of realistic human models for 7 T cardiac imaging
title_full_unstemmed SAR and temperature distributions in a database of realistic human models for 7 T cardiac imaging
title_short SAR and temperature distributions in a database of realistic human models for 7 T cardiac imaging
title_sort sar and temperature distributions in a database of realistic human models for 7 t cardiac imaging
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244032/
https://www.ncbi.nlm.nih.gov/pubmed/33955061
http://dx.doi.org/10.1002/nbm.4525
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