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Electrospray ionization mass spectrometry ion suppression/enhancement caused by column bleed for three mixed‐mode reversed‐phase/anion‐exchange high‐performance liquid chromatography columns

RATIONALE: Mixed‐mode reversed‐phase/anion exchange liquid chromatography is useful for separations of mixtures containing anions (e.g. ionized acids). However, when using this form of liquid chromatography with mass spectrometry detection, the bleed of amine‐containing hydrolysis products from the...

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Detalles Bibliográficos
Autores principales: Walter, Thomas H., Blaze M. T., Melvin, Boissel, Cheryl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244038/
https://www.ncbi.nlm.nih.gov/pubmed/33830546
http://dx.doi.org/10.1002/rcm.9098