Cargando…

A plug‐and‐play, lightweight, single‐axis gradient insert design for increasing spatiotemporal resolution in echo planar imaging‐based brain imaging

The goal of this study was to introduce and evaluate the performance of a lightweight, high‐performance, single‐axis (z‐axis) gradient insert design primarily intended for high‐resolution functional magnetic resonance imaging, and aimed at providing both ease of use and a boost in spatiotemporal res...

Descripción completa

Detalles Bibliográficos
Autores principales: Versteeg, Edwin, van der Velden, Tijl A., van Leeuwen, Carel C., Borgo, Martino, Huijing, Erik R., Hendriks, Arjan D., Hendrikse, Jeroen, Klomp, Dennis W. J., Siero, Jeroen C. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244051/
https://www.ncbi.nlm.nih.gov/pubmed/33619838
http://dx.doi.org/10.1002/nbm.4499
_version_ 1783715855101591552
author Versteeg, Edwin
van der Velden, Tijl A.
van Leeuwen, Carel C.
Borgo, Martino
Huijing, Erik R.
Hendriks, Arjan D.
Hendrikse, Jeroen
Klomp, Dennis W. J.
Siero, Jeroen C. W.
author_facet Versteeg, Edwin
van der Velden, Tijl A.
van Leeuwen, Carel C.
Borgo, Martino
Huijing, Erik R.
Hendriks, Arjan D.
Hendrikse, Jeroen
Klomp, Dennis W. J.
Siero, Jeroen C. W.
author_sort Versteeg, Edwin
collection PubMed
description The goal of this study was to introduce and evaluate the performance of a lightweight, high‐performance, single‐axis (z‐axis) gradient insert design primarily intended for high‐resolution functional magnetic resonance imaging, and aimed at providing both ease of use and a boost in spatiotemporal resolution. The optimal winding positions of the coil were obtained using a genetic algorithm with a cost function that balanced gradient performance (minimum 0.30 mT/m/A) and field linearity (≥16 cm linear region). These parameters were verified using field distribution measurements by B(0)‐mapping. The correction of geometrical distortions was performed using theoretical field distribution of the coil. Simulations and measurements were performed to investigate the echo planar imaging echo‐spacing reduction due to the improved gradient performance. The resulting coil featured a 16‐cm linear region, a weight of 45 kg, an installation time of 15 min, and a maximum gradient strength and slew rate of 200 mT/m and 1300 T/m/s, respectively, when paired with a commercially available gradient amplifier (940 V/630 A). The field distribution measurements matched the theoretically expected field. By utilizing the theoretical field distribution, geometrical distortions were corrected to within 6% of the whole‐body gradient reference image in the target region. Compared with a whole‐body gradient set, a maximum reduction in echo‐spacing of a factor of 2.3 was found, translating to a 344 μs echo‐spacing, for a field of view of 192 mm, a receiver bandwidth of 920 kHz and a gradient amplitude of 112 mT/m. We present a lightweight, single‐axis gradient insert design that can provide high gradient performance and an increase in spatiotemporal resolution with correctable geometrical distortions while also offering a short installation time of less than 15 min and minimal system modifications.
format Online
Article
Text
id pubmed-8244051
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-82440512021-07-02 A plug‐and‐play, lightweight, single‐axis gradient insert design for increasing spatiotemporal resolution in echo planar imaging‐based brain imaging Versteeg, Edwin van der Velden, Tijl A. van Leeuwen, Carel C. Borgo, Martino Huijing, Erik R. Hendriks, Arjan D. Hendrikse, Jeroen Klomp, Dennis W. J. Siero, Jeroen C. W. NMR Biomed Research Articles The goal of this study was to introduce and evaluate the performance of a lightweight, high‐performance, single‐axis (z‐axis) gradient insert design primarily intended for high‐resolution functional magnetic resonance imaging, and aimed at providing both ease of use and a boost in spatiotemporal resolution. The optimal winding positions of the coil were obtained using a genetic algorithm with a cost function that balanced gradient performance (minimum 0.30 mT/m/A) and field linearity (≥16 cm linear region). These parameters were verified using field distribution measurements by B(0)‐mapping. The correction of geometrical distortions was performed using theoretical field distribution of the coil. Simulations and measurements were performed to investigate the echo planar imaging echo‐spacing reduction due to the improved gradient performance. The resulting coil featured a 16‐cm linear region, a weight of 45 kg, an installation time of 15 min, and a maximum gradient strength and slew rate of 200 mT/m and 1300 T/m/s, respectively, when paired with a commercially available gradient amplifier (940 V/630 A). The field distribution measurements matched the theoretically expected field. By utilizing the theoretical field distribution, geometrical distortions were corrected to within 6% of the whole‐body gradient reference image in the target region. Compared with a whole‐body gradient set, a maximum reduction in echo‐spacing of a factor of 2.3 was found, translating to a 344 μs echo‐spacing, for a field of view of 192 mm, a receiver bandwidth of 920 kHz and a gradient amplitude of 112 mT/m. We present a lightweight, single‐axis gradient insert design that can provide high gradient performance and an increase in spatiotemporal resolution with correctable geometrical distortions while also offering a short installation time of less than 15 min and minimal system modifications. John Wiley and Sons Inc. 2021-02-22 2021-06 /pmc/articles/PMC8244051/ /pubmed/33619838 http://dx.doi.org/10.1002/nbm.4499 Text en © 2021 The Authors. NMR in Biomedicine published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Versteeg, Edwin
van der Velden, Tijl A.
van Leeuwen, Carel C.
Borgo, Martino
Huijing, Erik R.
Hendriks, Arjan D.
Hendrikse, Jeroen
Klomp, Dennis W. J.
Siero, Jeroen C. W.
A plug‐and‐play, lightweight, single‐axis gradient insert design for increasing spatiotemporal resolution in echo planar imaging‐based brain imaging
title A plug‐and‐play, lightweight, single‐axis gradient insert design for increasing spatiotemporal resolution in echo planar imaging‐based brain imaging
title_full A plug‐and‐play, lightweight, single‐axis gradient insert design for increasing spatiotemporal resolution in echo planar imaging‐based brain imaging
title_fullStr A plug‐and‐play, lightweight, single‐axis gradient insert design for increasing spatiotemporal resolution in echo planar imaging‐based brain imaging
title_full_unstemmed A plug‐and‐play, lightweight, single‐axis gradient insert design for increasing spatiotemporal resolution in echo planar imaging‐based brain imaging
title_short A plug‐and‐play, lightweight, single‐axis gradient insert design for increasing spatiotemporal resolution in echo planar imaging‐based brain imaging
title_sort plug‐and‐play, lightweight, single‐axis gradient insert design for increasing spatiotemporal resolution in echo planar imaging‐based brain imaging
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244051/
https://www.ncbi.nlm.nih.gov/pubmed/33619838
http://dx.doi.org/10.1002/nbm.4499
work_keys_str_mv AT versteegedwin aplugandplaylightweightsingleaxisgradientinsertdesignforincreasingspatiotemporalresolutioninechoplanarimagingbasedbrainimaging
AT vanderveldentijla aplugandplaylightweightsingleaxisgradientinsertdesignforincreasingspatiotemporalresolutioninechoplanarimagingbasedbrainimaging
AT vanleeuwencarelc aplugandplaylightweightsingleaxisgradientinsertdesignforincreasingspatiotemporalresolutioninechoplanarimagingbasedbrainimaging
AT borgomartino aplugandplaylightweightsingleaxisgradientinsertdesignforincreasingspatiotemporalresolutioninechoplanarimagingbasedbrainimaging
AT huijingerikr aplugandplaylightweightsingleaxisgradientinsertdesignforincreasingspatiotemporalresolutioninechoplanarimagingbasedbrainimaging
AT hendriksarjand aplugandplaylightweightsingleaxisgradientinsertdesignforincreasingspatiotemporalresolutioninechoplanarimagingbasedbrainimaging
AT hendriksejeroen aplugandplaylightweightsingleaxisgradientinsertdesignforincreasingspatiotemporalresolutioninechoplanarimagingbasedbrainimaging
AT klompdenniswj aplugandplaylightweightsingleaxisgradientinsertdesignforincreasingspatiotemporalresolutioninechoplanarimagingbasedbrainimaging
AT sierojeroencw aplugandplaylightweightsingleaxisgradientinsertdesignforincreasingspatiotemporalresolutioninechoplanarimagingbasedbrainimaging
AT versteegedwin plugandplaylightweightsingleaxisgradientinsertdesignforincreasingspatiotemporalresolutioninechoplanarimagingbasedbrainimaging
AT vanderveldentijla plugandplaylightweightsingleaxisgradientinsertdesignforincreasingspatiotemporalresolutioninechoplanarimagingbasedbrainimaging
AT vanleeuwencarelc plugandplaylightweightsingleaxisgradientinsertdesignforincreasingspatiotemporalresolutioninechoplanarimagingbasedbrainimaging
AT borgomartino plugandplaylightweightsingleaxisgradientinsertdesignforincreasingspatiotemporalresolutioninechoplanarimagingbasedbrainimaging
AT huijingerikr plugandplaylightweightsingleaxisgradientinsertdesignforincreasingspatiotemporalresolutioninechoplanarimagingbasedbrainimaging
AT hendriksarjand plugandplaylightweightsingleaxisgradientinsertdesignforincreasingspatiotemporalresolutioninechoplanarimagingbasedbrainimaging
AT hendriksejeroen plugandplaylightweightsingleaxisgradientinsertdesignforincreasingspatiotemporalresolutioninechoplanarimagingbasedbrainimaging
AT klompdenniswj plugandplaylightweightsingleaxisgradientinsertdesignforincreasingspatiotemporalresolutioninechoplanarimagingbasedbrainimaging
AT sierojeroencw plugandplaylightweightsingleaxisgradientinsertdesignforincreasingspatiotemporalresolutioninechoplanarimagingbasedbrainimaging