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A plug‐and‐play, lightweight, single‐axis gradient insert design for increasing spatiotemporal resolution in echo planar imaging‐based brain imaging
The goal of this study was to introduce and evaluate the performance of a lightweight, high‐performance, single‐axis (z‐axis) gradient insert design primarily intended for high‐resolution functional magnetic resonance imaging, and aimed at providing both ease of use and a boost in spatiotemporal res...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244051/ https://www.ncbi.nlm.nih.gov/pubmed/33619838 http://dx.doi.org/10.1002/nbm.4499 |
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author | Versteeg, Edwin van der Velden, Tijl A. van Leeuwen, Carel C. Borgo, Martino Huijing, Erik R. Hendriks, Arjan D. Hendrikse, Jeroen Klomp, Dennis W. J. Siero, Jeroen C. W. |
author_facet | Versteeg, Edwin van der Velden, Tijl A. van Leeuwen, Carel C. Borgo, Martino Huijing, Erik R. Hendriks, Arjan D. Hendrikse, Jeroen Klomp, Dennis W. J. Siero, Jeroen C. W. |
author_sort | Versteeg, Edwin |
collection | PubMed |
description | The goal of this study was to introduce and evaluate the performance of a lightweight, high‐performance, single‐axis (z‐axis) gradient insert design primarily intended for high‐resolution functional magnetic resonance imaging, and aimed at providing both ease of use and a boost in spatiotemporal resolution. The optimal winding positions of the coil were obtained using a genetic algorithm with a cost function that balanced gradient performance (minimum 0.30 mT/m/A) and field linearity (≥16 cm linear region). These parameters were verified using field distribution measurements by B(0)‐mapping. The correction of geometrical distortions was performed using theoretical field distribution of the coil. Simulations and measurements were performed to investigate the echo planar imaging echo‐spacing reduction due to the improved gradient performance. The resulting coil featured a 16‐cm linear region, a weight of 45 kg, an installation time of 15 min, and a maximum gradient strength and slew rate of 200 mT/m and 1300 T/m/s, respectively, when paired with a commercially available gradient amplifier (940 V/630 A). The field distribution measurements matched the theoretically expected field. By utilizing the theoretical field distribution, geometrical distortions were corrected to within 6% of the whole‐body gradient reference image in the target region. Compared with a whole‐body gradient set, a maximum reduction in echo‐spacing of a factor of 2.3 was found, translating to a 344 μs echo‐spacing, for a field of view of 192 mm, a receiver bandwidth of 920 kHz and a gradient amplitude of 112 mT/m. We present a lightweight, single‐axis gradient insert design that can provide high gradient performance and an increase in spatiotemporal resolution with correctable geometrical distortions while also offering a short installation time of less than 15 min and minimal system modifications. |
format | Online Article Text |
id | pubmed-8244051 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82440512021-07-02 A plug‐and‐play, lightweight, single‐axis gradient insert design for increasing spatiotemporal resolution in echo planar imaging‐based brain imaging Versteeg, Edwin van der Velden, Tijl A. van Leeuwen, Carel C. Borgo, Martino Huijing, Erik R. Hendriks, Arjan D. Hendrikse, Jeroen Klomp, Dennis W. J. Siero, Jeroen C. W. NMR Biomed Research Articles The goal of this study was to introduce and evaluate the performance of a lightweight, high‐performance, single‐axis (z‐axis) gradient insert design primarily intended for high‐resolution functional magnetic resonance imaging, and aimed at providing both ease of use and a boost in spatiotemporal resolution. The optimal winding positions of the coil were obtained using a genetic algorithm with a cost function that balanced gradient performance (minimum 0.30 mT/m/A) and field linearity (≥16 cm linear region). These parameters were verified using field distribution measurements by B(0)‐mapping. The correction of geometrical distortions was performed using theoretical field distribution of the coil. Simulations and measurements were performed to investigate the echo planar imaging echo‐spacing reduction due to the improved gradient performance. The resulting coil featured a 16‐cm linear region, a weight of 45 kg, an installation time of 15 min, and a maximum gradient strength and slew rate of 200 mT/m and 1300 T/m/s, respectively, when paired with a commercially available gradient amplifier (940 V/630 A). The field distribution measurements matched the theoretically expected field. By utilizing the theoretical field distribution, geometrical distortions were corrected to within 6% of the whole‐body gradient reference image in the target region. Compared with a whole‐body gradient set, a maximum reduction in echo‐spacing of a factor of 2.3 was found, translating to a 344 μs echo‐spacing, for a field of view of 192 mm, a receiver bandwidth of 920 kHz and a gradient amplitude of 112 mT/m. We present a lightweight, single‐axis gradient insert design that can provide high gradient performance and an increase in spatiotemporal resolution with correctable geometrical distortions while also offering a short installation time of less than 15 min and minimal system modifications. John Wiley and Sons Inc. 2021-02-22 2021-06 /pmc/articles/PMC8244051/ /pubmed/33619838 http://dx.doi.org/10.1002/nbm.4499 Text en © 2021 The Authors. NMR in Biomedicine published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Articles Versteeg, Edwin van der Velden, Tijl A. van Leeuwen, Carel C. Borgo, Martino Huijing, Erik R. Hendriks, Arjan D. Hendrikse, Jeroen Klomp, Dennis W. J. Siero, Jeroen C. W. A plug‐and‐play, lightweight, single‐axis gradient insert design for increasing spatiotemporal resolution in echo planar imaging‐based brain imaging |
title | A plug‐and‐play, lightweight, single‐axis gradient insert design for increasing spatiotemporal resolution in echo planar imaging‐based brain imaging |
title_full | A plug‐and‐play, lightweight, single‐axis gradient insert design for increasing spatiotemporal resolution in echo planar imaging‐based brain imaging |
title_fullStr | A plug‐and‐play, lightweight, single‐axis gradient insert design for increasing spatiotemporal resolution in echo planar imaging‐based brain imaging |
title_full_unstemmed | A plug‐and‐play, lightweight, single‐axis gradient insert design for increasing spatiotemporal resolution in echo planar imaging‐based brain imaging |
title_short | A plug‐and‐play, lightweight, single‐axis gradient insert design for increasing spatiotemporal resolution in echo planar imaging‐based brain imaging |
title_sort | plug‐and‐play, lightweight, single‐axis gradient insert design for increasing spatiotemporal resolution in echo planar imaging‐based brain imaging |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244051/ https://www.ncbi.nlm.nih.gov/pubmed/33619838 http://dx.doi.org/10.1002/nbm.4499 |
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