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Methylation status of genes escaping from X-chromosome inactivation in patients with X-chromosome rearrangements

BACKGROUND: X-chromosome inactivation (XCI) is a mechanism in which one of two X chromosomes in females is randomly inactivated in order to compensate for imbalance of gene dosage between sexes. However, about 15% of genes on the inactivated X chromosome (Xi) escape from XCI. The methylation level o...

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Detalles Bibliográficos
Autores principales:	Kawashima, Sayaka, Hattori, Atsushi, Suzuki, Erina, Matsubara, Keiko, Toki, Machiko, Kosaki, Rika, Hasegawa, Yukihiro, Nakabayashi, Kazuhiko, Fukami, Maki, Kagami, Masayo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244138/ https://www.ncbi.nlm.nih.gov/pubmed/34193245 http://dx.doi.org/10.1186/s13148-021-01121-6

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