Cargando…

Mesenchymal stem cell-derived extracellular vesicles prevent the development of osteoarthritis via the circHIPK3/miR-124-3p/MYH9 axis

BACKGROUND: Extracellular vesicles (EVs) secreted by mesenchymal stem cells (MSCs) may play a vital role in a variety of biological processes, including cartilage regeneration. However, few studies reported their potential in the development of osteoarthritis (OA) previously. In this study, we explo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Shenglong, Liu, Jie, Liu, Siyu, Jiao, Weijie, Wang, Xiaohong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244143/ https://www.ncbi.nlm.nih.gov/pubmed/34193158 http://dx.doi.org/10.1186/s12951-021-00940-2

Ejemplares similares

CircHIPK3 Plays Vital Roles in Cardiovascular Disease
por: Zhang, Lei, et al.
Publicado: (2021)

Biogenesis, cellular effects, and biomarker value of circHIPK3
por: Fu, Yihan, et al.
Publicado: (2021)

Circular RNA circHIPK3 is downregulated in diabetic cardiomyopathy and overexpression of circHIPK3 suppresses PTEN to protect cardiomyocytes from high glucose-induced cell apoptosis
por: Jiang, Jun, et al.
Publicado: (2022)

Understanding the Dual Roles of CircHIPK3 in Tumorigenesis and Tumor Progression
por: Wei, Zeyu, et al.
Publicado: (2022)

Serum Extracellular Vesicle-Derived circHIPK3 and circSMARCA5 Are Two Novel Diagnostic Biomarkers for Glioblastoma Multiforme
por: Stella, Michele, et al.
Publicado: (2021)

CircHIPK3: Key Player in Pathophysiology and Potential Diagnostic and Therapeutic Tool
por: Zhou, Jiang, et al.
Publicado: (2021)

CircHIPK2 promotes proliferation of nasopharyngeal carcinoma by down-regulating HIPK2
por: Zhang, Dan, et al.
Publicado: (2022)

circHIPK3 regulates cell proliferation and migration by sponging miR-124 and regulating AQP3 expression in hepatocellular carcinoma
por: Chen, Genwen, et al.
Publicado: (2018)

Circular RNA CircHIPK3 Promotes Gemcitabine Sensitivity in Bladder Cancer
por: Xie, Fang, et al.
Publicado: (2020)

Emerging landscape of circHIPK3 and its role in cancer and other diseases
por: Shao, Qi, et al.
Publicado: (2021)

Regulation of Podocyte Injury by CircHIPK3/FUS Complex in Diabetic Kidney Disease
por: Liu, Feng, et al.
Publicado: (2022)

Circular RNA CircHIPK3 Elevates CCND2 Expression and Promotes Cell Proliferation and Invasion Through miR-124 in Glioma
por: Liu, Zengjin, et al.
Publicado: (2020)

Down-regulation of circular RNA ITCH and circHIPK3 in gastric cancer tissues
por: GHASEMI, Sara, et al.
Publicado: (2018)

Mechanism of RNA circHIPK3 Involved in Resistance of Lung Cancer Cells to Gefitinib
por: Zhao, Yi, et al.
Publicado: (2022)

CircHIPK3 promotes colorectal cancer growth and metastasis by sponging miR-7
por: Zeng, Kaixuan, et al.
Publicado: (2018)

Circular RNA circHIPK3 Promotes Cell Metastasis through miR-637/STAT3 Axis in Osteosarcoma
por: Huang, Zhongyue, et al.
Publicado: (2020)

Dysregulation of the miR‐30c/DLL4 axis by circHIPK3 is essential for KSHV lytic replication
por: Harper, Katherine L, et al.
Publicado: (2022)

CircHIPK3 Promotes Pyroptosis in Acinar Cells Through Regulation of the miR-193a-5p/GSDMD Axis
por: Wang, Jiale, et al.
Publicado: (2020)

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs
por: Zheng, Qiupeng, et al.
Publicado: (2016)

Circular RNA circ_HIPK3 is down-regulated and suppresses cell proliferation, migration and invasion in osteosarcoma
por: Xiao-Long, Ma, et al.
Publicado: (2018)

circHIPK3 regulates lung fibroblast-to-myofibroblast transition by functioning as a competing endogenous RNA
por: Zhang, Jia-xiang, et al.
Publicado: (2019)

circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA
por: Okholm, Trine Line Hauge, et al.
Publicado: (2023)

CircHIPK3 negatively regulates autophagy by blocking VCP binding to the Beclin 1 complex in bladder cancer
por: Wang, Chong, et al.
Publicado: (2023)

circHIPK3 promotes oxaliplatin-resistance in colorectal cancer through autophagy by sponging miR-637
por: Zhang, Yanli, et al.
Publicado: (2019)

BMSC-Derived Exosomal CircHIPK3 Promotes Osteogenic Differentiation of MC3T3-E1 Cells via Mitophagy
por: Ma, Shaoyang, et al.
Publicado: (2023)

Regulation of MRP4 Expression by circHIPK3 via Sponging miR-124-3p/miR-4524-5p in Hepatocellular Carcinoma
por: Hu, Haihong, et al.
Publicado: (2021)

circHIPK3 regulates cell proliferation and migration by sponging microRNA-124 and regulating serine/threonine kinase 3 expression in esophageal squamous cell carcinoma
por: Yao, Da, et al.
Publicado: (2022)

circHIPK3 Exacerbates Folic Acid-Induced Renal Tubulointerstitial Fibrosis by Sponging miR-30a
por: Wu, Yan, et al.
Publicado: (2022)

CircHIPK2 Contributes to DDP Resistance and Malignant Behaviors of DDP-Resistant Ovarian Cancer Cells Both in vitro and in vivo Through circHIPK2/miR-338-3p/CHTOP ceRNA Pathway
por: Cao, Yang, et al.
Publicado: (2021)

Exosomal CircHIPK3 Released from Hypoxia-Induced Cardiomyocytes Regulates Cardiac Angiogenesis after Myocardial Infarction
por: Wang, Yan, et al.
Publicado: (2020)

circHIPK3 prevents cardiac senescence by acting as a scaffold to recruit ubiquitin ligase to degrade HuR
por: Ding, Fengzhi, et al.
Publicado: (2022)

Prolactin-Responsive Circular RNA circHIPK3 Promotes Proliferation of Mammary Epithelial Cells from Dairy Cow
por: Liu, Jia, et al.
Publicado: (2020)

circHIPK3 (hsa_circ_0000284) Promotes Proliferation, Migration and Invasion of Breast Cancer Cells via miR-326
por: Qi, Liqiang, et al.
Publicado: (2021)

Circular RNA circHIPK3 Promotes the Proliferation and Differentiation of Chicken Myoblast Cells by Sponging miR-30a-3p
por: Chen, Biao, et al.
Publicado: (2019)

CircHIPK3 Facilitates the G2/M Transition in Prostate Cancer Cells by Sponging miR-338-3p
por: Liu, Fengchun, et al.
Publicado: (2020)

CircHIPK3 regulates cardiac fibroblast proliferation, migration and phenotypic switching through the miR-152-3p/TGF-β2 axis under hypoxia
por: Liu, Weiwei, et al.
Publicado: (2020)

CircHIPK3 Promotes the Tumorigenesis and Development of Gastric Cancer Through miR-637/AKT1 Pathway
por: Yang, Dejun, et al.
Publicado: (2021)

CircHIPK3 regulates the autophagy and apoptosis of hypoxia/reoxygenation-stimulated cardiomyocytes via the miR-20b-5p/ATG7 axis
por: Qiu, Zhimei, et al.
Publicado: (2021)

CircHIPK3 regulates pulmonary fibrosis by facilitating glycolysis in miR-30a-3p/FOXK2-dependent manner
por: Xu, Qi, et al.
Publicado: (2021)

Sp1-Mediated circRNA circHipk2 Regulates Myogenesis by Targeting Ribosomal Protein Rpl7
por: Yan, Junyu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_3lps70brjoluqpr91bfnrnuc0e