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A novel DNA methylation signature is associated with androgen receptor activity and patient prognosis in bone metastatic prostate cancer

BACKGROUND: Patients with metastatic prostate cancer (PC) are treated with androgen deprivation therapy (ADT) that initially reduces metastasis growth, but after some time lethal castration-resistant PC (CRPC) develops. A better understanding of the tumor biology in bone metastases is needed to guid...

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Detalles Bibliográficos
Autores principales: Ylitalo, Erik Bovinder, Thysell, Elin, Landfors, Mattias, Brattsand, Maria, Jernberg, Emma, Crnalic, Sead, Widmark, Anders, Hultdin, Magnus, Bergh, Anders, Degerman, Sofie, Wikström, Pernilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244194/
https://www.ncbi.nlm.nih.gov/pubmed/34193246
http://dx.doi.org/10.1186/s13148-021-01119-0

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