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A systems pharmacology approach based on oncogenic signalling pathways to determine the mechanisms of action of natural products in breast cancer from transcriptome data

BACKGROUND: Narrow spectrum of action through limited molecular targets and unforeseen drug-related toxicities have been the main reasons for drug failures at the phase I clinical trials in complex diseases. Most plant-derived compounds with medicinal values possess poly-pharmacologic properties wit...

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Detalles Bibliográficos
Autores principales:	Odongo, Regan, Demiroglu-Zergeroglu, Asuman, Çakır, Tunahan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244196/ https://www.ncbi.nlm.nih.gov/pubmed/34193143 http://dx.doi.org/10.1186/s12906-021-03340-z

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