Comprehensive high-throughput meta-analysis of differentially expressed microRNAs in transcriptomic datasets reveals significant disruption of MAPK/JNK signal transduction pathway in Adult T-cell leukemia/lymphoma

BACKGROUND: Human T-lymphotropic virus 1 (HTLV-1) infection may lead to the development of Adult T-cell leukemia/lymphoma (ATLL). To further elucidate the pathophysiology of this aggressive CD4+ T-cell malignancy, we have performed an integrated systems biology approach to analyze previous transcrip...

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Detalles Bibliográficos
Autores principales: Shadabi, Shahrzad, Delrish, Nargess, Norouzi, Mehdi, Ehteshami, Maryam, Habibian-Sezavar, Fariba, Pourrezaei, Samira, Madihi, Mobina, Ostadali, Mohammadreza, Akhgar, Foruhar, Shayeghpour, Ali, Razavi Pashabayg, Cobra, Aghajanian, Sepehr, Mozhgani, Sayed-Hamidreza, Jazayeri, Seyed-Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244200/
https://www.ncbi.nlm.nih.gov/pubmed/34187521
http://dx.doi.org/10.1186/s13027-021-00390-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244200/
https://www.ncbi.nlm.nih.gov/pubmed/34187521
http://dx.doi.org/10.1186/s13027-021-00390-3

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