Closed-loop neuromodulation will increase the utility of mouse models in Bioelectronic Medicine

Mouse models have been of tremendous benefit to medical science for the better part of a century, yet bioelectronic medicine research using mice has been limited to mostly acute studies because of a lack of tools for chronic stimulation and sensing. A wireless neuromodulation platform small enough f...

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Autor principal: Datta-Chaudhuri, Timir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244222/
https://www.ncbi.nlm.nih.gov/pubmed/34193309
http://dx.doi.org/10.1186/s42234-021-00071-x
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author Datta-Chaudhuri, Timir
author_facet Datta-Chaudhuri, Timir
author_sort Datta-Chaudhuri, Timir
collection PubMed
description Mouse models have been of tremendous benefit to medical science for the better part of a century, yet bioelectronic medicine research using mice has been limited to mostly acute studies because of a lack of tools for chronic stimulation and sensing. A wireless neuromodulation platform small enough for implantation in mice will significantly increase the utility of mouse models in bioelectronic medicine. This perspective examines the necessary functionality of such a system and the technical challenges needed to be overcome for its development. Recent progress is examined and the outlook for the future of implantable devices for mice is discussed.
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spelling pubmed-82442222021-06-30 Closed-loop neuromodulation will increase the utility of mouse models in Bioelectronic Medicine Datta-Chaudhuri, Timir Bioelectron Med Perspective Mouse models have been of tremendous benefit to medical science for the better part of a century, yet bioelectronic medicine research using mice has been limited to mostly acute studies because of a lack of tools for chronic stimulation and sensing. A wireless neuromodulation platform small enough for implantation in mice will significantly increase the utility of mouse models in bioelectronic medicine. This perspective examines the necessary functionality of such a system and the technical challenges needed to be overcome for its development. Recent progress is examined and the outlook for the future of implantable devices for mice is discussed. BioMed Central 2021-06-30 /pmc/articles/PMC8244222/ /pubmed/34193309 http://dx.doi.org/10.1186/s42234-021-00071-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Perspective
Datta-Chaudhuri, Timir
Closed-loop neuromodulation will increase the utility of mouse models in Bioelectronic Medicine
title Closed-loop neuromodulation will increase the utility of mouse models in Bioelectronic Medicine
title_full Closed-loop neuromodulation will increase the utility of mouse models in Bioelectronic Medicine
title_fullStr Closed-loop neuromodulation will increase the utility of mouse models in Bioelectronic Medicine
title_full_unstemmed Closed-loop neuromodulation will increase the utility of mouse models in Bioelectronic Medicine
title_short Closed-loop neuromodulation will increase the utility of mouse models in Bioelectronic Medicine
title_sort closed-loop neuromodulation will increase the utility of mouse models in bioelectronic medicine
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244222/
https://www.ncbi.nlm.nih.gov/pubmed/34193309
http://dx.doi.org/10.1186/s42234-021-00071-x
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